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HOPX Products

(HOP Homeobox (HOPX))

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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009].

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Featured HOPX Categories

HOPX Antibodies

High quality antibodies with extensive validation data.

HOPX Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HOPX Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (1)
  • (2)
Cat. No. ABIN655402
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7444223
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IHC (p)
Validations
  • (2)
Cat. No. ABIN1387281
Quantity 100 μL
Datasheet Datasheet

Recommended HOPX ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967461
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210509
Quantity 96 tests
Datasheet Datasheet

Recommended HOPX Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
  • (1)
Cat. No. ABIN1686718
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306912
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129765
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HOPX products

Chen, Yang, Cui, Pacyna-Gengelbach, Petersen: "HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer." in: The Journal of pathology, Vol. 235, Issue 3, pp. 397-407, (2015) (PubMed).

Wahyudi, Wang, McAlpine: "Dimerization of a heat shock protein 90 inhibitor enhances inhibitory activity." in: Organic & biomolecular chemistry, Vol. 12, Issue 5, pp. 765-73, (2014) (PubMed).

Kovárová, Plachy, Kosla, Trejbalová, ?ermák, Hejnar: "Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis." in: Molecular cancer research : MCR, Vol. 11, Issue 10, pp. 1235-47, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Willmer, Contu, Blatch, Edkins: "Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines." in: Cancer letters, Vol. 328, Issue 2, pp. 252-60, (2012) (PubMed).

Synonyms and alternative names related to HOPX

HOP homeobox (HOPX), HOP homeobox (Hopx), HOP homeobox (hopx), 1110018K11Rik, 1200015P04Rik, 2300002F06Rik, AI848177, AW490897, CAMEO, Cameo, cameo, GIIg15b, Hdop, HOD, Hod, hod, HOP, Hop, hop, HOPX, LAGY, lagy, MGC147344, NECC1, necc1, OB1, Ob1, ob1, Obl, SMAP31, smap31, TOTO, Toto, toto

Protein level used designations for HOPX

  • homeodomain-only protein
  • lung cancer-associated Y protein
  • not expressed in choriocarcinoma clone 1
  • not expressed in choriocarcinoma protein 1
  • odd homeobox 1 protein
  • odd homeobox protein 1
  • homeobox only domain
  • homeobox-only protein
  • homeodomain only protein
  • mOB1
  • odd homeobox 1
  • global ischemia induced protein GIIG15B
  • global ischemia-induced gene 15B protein
  • global ischemia-induced protein 15B
  • HOP homeobox
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