HOGA1 Products
(4-Hydroxy-2-Oxoglutarate Aldolase 1 (HOGA1))
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The authors of PMID searching for genes in a region of chromosome 10 linked to primary hyperoxalurea type III. They noted that even though the encoded protein has been described as a mitochondrial dihydrodipicolinate synthase-like enzyme, it shares little homology with E. coli dihydrodipicolinate synthase (Dhdps), particularly in the putative substrate-binding region. Moreover, neither lysine biosynthesis nor sialic acid metabolism, for which Dhdps is responsible, occurs in vertebrate mitochondria. They propose that this gene encodes mitochondrial 4-hydroxyl-2-oxoglutarate aldolase (EC 4.1.3.16), which catalyzes the final step in the metabolic pathway of hydroxyproline, releasing glyoxylate and pyruvate. This gene is predominantly expressed in the liver and kidney, and mutations in this gene are found in patients with primary hyperoxalurea type III. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Nov 2010].
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Featured HOGA1 Categories
HOGA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HOGA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HOGA1 Antibodies
Recommended HOGA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964476
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971236
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1149335
Quantity
96 tests
Datasheet
Datasheet
Recommended HOGA1 Proteins
Synonyms and alternative names related to HOGA1
4-hydroxy-2-oxoglutarate aldolase 1 (HOGA1), 4-hydroxy-2-oxoglutarate aldolase 1 (Hoga1), 0610010D20Rik, C10orf65, DHDPS2, DHDPSL, Dhdpsl, HP3, NPL2, Npl2Protein level used designations for HOGA1
- DHDPS-like protein
- N-acetylneuraminate pyruvate lyase 2 (putative)
- dihydrodipicolinate synthase-like, mitochondrial
- dihydrodipicolinate synthetase homolog 2
- probable 2-keto-4-hydroxyglutarate aldolase
- probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
- probable KHG-aldolase
- protein 569272
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