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HNRNPL Products

(Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Categories

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured HNRNPL Categories

HNRNPL Antibodies

High quality antibodies with extensive validation data.

HNRNPL ELISA Kits

Reliable ELISA kits for a wide range of species.

HNRNPL Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HNRNPL Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6141915
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC, IF, IP
Validations
  • (8)
Cat. No. ABIN2778777
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6262324
Quantity 100 μL
Datasheet Datasheet

Recommended HNRNPL ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow
Analytical Method Quantitative
Validations
Cat. No. ABIN1054703
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1054705
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN1054710
Quantity 96 tests
Datasheet Datasheet

Recommended HNRNPL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2566104
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092946
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126544
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HNRNPL products

Yao, Wu, Lindner, Fox: "Interplay between miR-574-3p and hnRNP L regulates VEGFA mRNA translation and tumorigenesis." in: Nucleic acids research, Vol. 45, Issue 13, pp. 7950-7964, (2017) (PubMed).

Li, Collins, An, Geiser, Tegeler, Tsantilas, Garcia, Pirrotte, Bowser: "Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network." in: Brain research, Vol. 1647, pp. 79-93, (2016) (PubMed).

Yao, Potdar, Ray, Eswarappa, Flagg, Willard, Fox: "The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA." in: PLoS biology, Vol. 11, Issue 8, pp. e1001635, (2013) (PubMed).

Peddigari, Li, Rabe, Martin: "hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition." in: Nucleic acids research, Vol. 41, Issue 1, pp. 575-85, (2012) (PubMed).

Marzano, Santini, Rossi, Zucchelli, DAlessandro, Marchetti, Mingardi, Stagni, Barilà, Urbani: "Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity." in: Journal of proteomics, Vol. 75, Issue 15, pp. 4632-46, (2012) (PubMed).

Malik-Soni, Frappier: "Proteomic profiling of EBNA1-host protein interactions in latent and lytic Epstein-Barr virus infections." in: Journal of virology, Vol. 86, Issue 12, pp. 6999-7002, (2012) (PubMed).

Motta-Mena, Smith, Mallory, Jackson, Wang, Lynch: "A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs)." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 20043-53, (2011) (PubMed).

Tsai, Wang, Huang, Waterman: "Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 4, pp. M110.007385, (2011) (PubMed).

Heyd, Lynch: "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing." in: Molecular cell, Vol. 40, Issue 1, pp. 126-37, (2010) (PubMed).

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Synonyms and alternative names related to HNRNPL

heterogeneous nuclear ribonucleoprotein L (HNRNPL), heterogeneous nuclear ribonucleoprotein L (hnrpl), heterogeneous nuclear ribonucleoprotein L (hnrnpl), heterogeneous nuclear ribonucleoprotein L (Hnrnpl), C79783, D830027H13Rik, hnRNP-L, hnrnp-L, HNRNPL, HNRPL, hnrpl, Hnrpl, zgc:55429

Protein level used designations for HNRNPL

  • hnRNP L
  • heterogeneous nuclear ribonucleoprotein L
  • Heterogeneous nuclear ribonucleoprotein L
  • heterogenous nuclear ribonucleoprotein L
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