HMGCS2 Products
(3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
Categories
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
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Featured HMGCS2 Categories
HMGCS2 Antibodies
High quality antibodies with extensive validation data.
HMGCS2 ELISA Kits
Reliable ELISA kits for a wide range of species.
HMGCS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HMGCS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7257752
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7265329
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7156004
Quantity
100 μg
Datasheet
Datasheet
Recommended HMGCS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN419363
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN779074
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1049620
Quantity
96 tests
Datasheet
Datasheet
Recommended HMGCS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306820
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306818
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5505541
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our HMGCS2 products
: "Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress." in: Cell research, Vol. 26, Issue 10, pp. 1112-1130, (2017) (PubMed).: "Metabolic Adaptation of the Small Intestine to Short- and Medium-Term High-Fat Diet Exposure." in: Journal of cellular physiology, Vol. 232, Issue 1, pp. 167-75, (2016) (PubMed).
: "Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-? agonist Wy-14643 in high-fat diet fed rats." in: PLoS ONE, Vol. 8, Issue 9, pp. e74869, (2013) (PubMed).
: "Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate." in: Journal of lipid research, Vol. 54, Issue 3, pp. 592-601, (2013) (PubMed).
: "Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line." in: The Journal of biological chemistry, Vol. 286, Issue 23, pp. 20423-30, (2011) (PubMed).
Synonyms and alternative names related to HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2), 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (Hmgcs2), hydroxymethylglutaryl-CoA synthase (mvaS), hydroxymethylglutaryl-CoA synthase (CNC05080), hydroxymethylglutaryl-coa synthase (HMCS1), hydroxymethylglutaryl-CoA synthase (hgsA), hydroxymethylglutaryl-CoA synthase (MFER_RS00425), hydroxymethylglutaryl-CoA synthase (LOC100285783), 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 (ECU10_0510), 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Eint_100450), 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Hmgcs2), 1300002P16, DDBDRAFT_0219349, DDBDRAFT_0219924, DDB_0219349, DDB_0219924, hmgCoA, Hmgcs1, mHS, Mt3h3mgProtein level used designations for HMGCS2
- 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
- HMG-CoA synthase
- hydroxymethylglutaryl-CoA synthase, mitochondrial
- 3-hydroxy-3-methylglutaryl coenzyme A synthase
- 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
- hydroxymethylglutaryl-CoA synthase 2
- hydroxymethylglutaryl-CoA synthase, mitochondrial-like
- hydroxymethylglutaryl-CoA synthase
- hydroxymethylglutaryl-coa synthase
- GRMZM2G106263
- putative hydroxymethylglutaryl-CoA synthase family protein
- 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2
- 3-hydroxy-3-methylglutaryl-CoA synthase 2
- 3-hydroxy-3-methylglutary-Coenzyme A synthase 2
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