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HLTF Products

(Helicase-Like Transcription Factor (HLTF))
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008].

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Featured HLTF Categories

HLTF Antibodies

High quality antibodies with extensive validation data.

HLTF ELISA Kits

Reliable ELISA kits for a wide range of species.

HLTF Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HLTF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7443560
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (3)
Cat. No. ABIN7154943
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN390787
Quantity 400 μL
Datasheet Datasheet

Recommended HLTF ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1115373
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1115372
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1136265
Quantity 96 tests
Datasheet Datasheet

Recommended HLTF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306775
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416901
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416964
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HLTF products

Ali, Biswas, Pal: "HSF1 mediated TNF-α production during proteotoxic stress response pioneers proinflammatory signal in human cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 2, pp. 2621-2635, (2019) (PubMed).

Paul, Ghosh, Mandal, Sau, Pal: "NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells." in: The Journal of biological chemistry, Vol. 293, Issue 50, pp. 19303-19316, (2018) (PubMed).

Arcolia, Paci, Dhont, Chantrain, Sirtaine, Decaestecker, Remmelink, Belayew, Saussez: "Helicase-like transcription factor: a new marker of well-differentiated thyroid cancers." in: BMC cancer, Vol. 14, pp. 492, (2014) (PubMed).

Oh, Gao, Lee, Ceglia, Seo, Zhang, Ahn, Chait, Patel, Kim, Greengard: "SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action." in: Cell, Vol. 152, Issue 4, pp. 831-43, (2013) (PubMed).

Helmer, Foreman, Dertien, Panchoo, Bhakta, Chilton: "Role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain." in: PLoS ONE, Vol. 8, Issue 6, pp. e66799, (2013) (PubMed).

Visser, Kayser, Palstra: "HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter." in: Genome research, Vol. 22, Issue 3, pp. 446-55, (2012) (PubMed).

Motegi, Liaw, Lee, Roest, Maas, Wu, Moinova, Markowitz, Ding, Hoeijmakers, Myung: "Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 34, pp. 12411-6, (2008) (PubMed).

Sheridan, Schorpp, Voz, Jones: "Cloning of an SNF2/SWI2-related protein that binds specifically to the SPH motifs of the SV40 enhancer and to the HIV-1 promoter." in: The Journal of biological chemistry, Vol. 270, Issue 9, pp. 4575-87, (1995) (PubMed).

Synonyms and alternative names related to HLTF

helicase like transcription factor (HLTF), helicase-like transcription factor (hltf), helicase-like transcription factor L homeolog (hltf.L), helicase like transcription factor (hltf), helicase-like transcription factor (Hltf), helicase like transcription factor (Hltf), AF010600, BC057116, HIP116, HIP116A, HLTF, HLTF1, MGC131155, P113, RNF80, RUSH, smarca3, SMARCA3, Smarca3, SNF2L3, Snf2l3, wu:fc33f07, ZBU1

Protein level used designations for HLTF

  • helicase-like transcription factor
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3
  • DNA-binding protein/plasminogen activator inhibitor 1 regulator
  • DNA-binding protein/plasminogen activator inhibitor-1 regulator
  • RING finger protein 80
  • SNF2-like 3
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3
  • sucrose nonfermenting protein 2-like 3
  • sucrose nonfermenting-like 3
  • RUSH 1
  • RUSH-1
  • TNF-response element-binding protein
  • helicase-like transcription factor-like protein
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