HLCS Products
(Biotin-Protein Ligase (HLCS))
Categories
This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011].
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Featured HLCS Categories
HLCS Antibodies
High quality antibodies with extensive validation data.
HLCS ELISA Kits
Reliable ELISA kits for a wide range of species.
HLCS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HLCS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7145611
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN947972
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN561280
Quantity
50 μL
Datasheet
Datasheet
Recommended HLCS ELISA Kits
Recommended HLCS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306769
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306771
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423054
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HLCS products
: "Enhanced in vivo imaging of metabolically biotinylated cell surface reporters." in: Analytical chemistry, Vol. 83, Issue 3, pp. 994-9, (2011) (PubMed).: "Distinct amino termini of two human HCS isoforms influence biotin acceptor substrate recognition." in: The Journal of biological chemistry, Vol. 284, Issue 45, pp. 30862-70, (2009) (PubMed).
Synonyms and alternative names related to HLCS
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) (Hlcs), holocarboxylase synthetase (HLCS), holocarboxylase synthetase (Hlcs), 410I21.SP6, D16Jhu34, HCS, RGD1565360Protein level used designations for HLCS
- biotin apo-protein ligase
- biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase
- biotin--protein ligase
- biotin--[acetyl-CoA-carboxylase] ligase
- biotin--[methylcrotonoyl-CoA-carboxylase] ligase
- biotin--[methylmalonyl-CoA-carboxytransferase] ligase
- holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
- holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
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