HLAG Products
(HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
Categories
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008].
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Featured HLAG Categories
HLAG Antibodies
High quality antibodies with extensive validation data.
HLAG ELISA Kits
Reliable ELISA kits for a wide range of species.
HLAG Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HLAG Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (fro), IHC (p)
Validations
- (10)
- (5)
Cat. No.
ABIN94366
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (11)
- (5)
Cat. No.
ABIN94373
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, IHC (fro), IP, ICC
Validations
- (15)
- (4)
Cat. No.
ABIN94369
Quantity
0.1 mg
Datasheet
Datasheet
Recommended HLAG ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6956586
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962367
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN809034
Quantity
96 tests
Datasheet
Datasheet
Recommended HLAG Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7274817
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274813
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274818
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HLAG products
: "An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells." in: Current protocols in stem cell biology, Vol. 50, Issue 1, pp. e96, (2020) (PubMed).: "Characterization of HLA-G Regulation and HLA Expression in Breast Cancer and Malignant Melanoma Cell Lines upon IFN-γ Stimulation and Inhibition of DNA Methylation." in: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).
: "Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis." in: American journal of human genetics, Vol. 105, Issue 6, pp. 1262-1273, (2019) (PubMed).
: "Circulating fetal and total cell-free DNA, and sHLA-G in black South African women with gestational hypertension and pre-eclampsia." in: Hypertension in pregnancy, Vol. 36, Issue 4, pp. 295-301, (2018) (PubMed).
: "T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G." in: Oncotarget, Vol. 9, Issue 5, pp. 6536-6549, (2018) (PubMed).
: "Mesenchymal stem cells upregulate Treg cells via sHLA-G in SLE patients." in: International immunopharmacology, Vol. 44, pp. 234-241, (2017) (PubMed).
: "Notch1 controls development of the extravillous trophoblast lineage in the human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 48, pp. E7710-E7719, (2016) (PubMed).
: "EPHB4 Regulates Human Trophoblast Cell Line HTR-8/SVneo Function: Implications for the Role of EPHB4 in Preeclampsia." in: Biology of reproduction, Vol. 95, Issue 3, pp. 65, (2016) (PubMed).
: "Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients." in: Cellular immunology, Vol. 293, Issue 1, pp. 10-6, (2015) (PubMed).
: "Clinical correlates of human leucocyte antigen (HLA)-G in systemic sclerosis." in: Clinical and experimental immunology, Vol. 181, Issue 1, pp. 100-9, (2015) (PubMed).
Synonyms and alternative names related to HLAG
major histocompatibility complex, class I, G (HLA-G), MHC BF1 class I (BF1), B-F, B-F-S04, B-F-S05, B-F-S06, B-F-S07, B-FI, B-FIV, BF2, BFa2, BFw-03, BFw-05, BFz-01, MHC-GProtein level used designations for HLAG
- HLA G antigen
- HLA class I histocompatibility antigen, alpha chain G
- HLA class I molecule
- HLA-G histocompatibility antigen, class I, G
- MHC class I antigen G
- b2 microglobulin
- B-F minor
- MHC class I antigen alpha chain
- MHC class I glycoprotein
- major histocompatibility complex, class I, G
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