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HLA-DRB4 Proteins

(Major Histocompatibility Complex, Class II, DR beta 4 (HLA-DRB4))
HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].
HLA-DRB4 Protein (AA 30-266) (GST tag) HLA-DRB4 Protein (AA 30-266) (GST tag) HLA-DRB4 Protein (AA 30-266) (GST tag) (ABIN1306767)

HLA-DRB4 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB

HLA-DRB4 Protein (Myc-DYKDDDDK Tag) HLA-DRB4 Protein (Myc-DYKDDDDK Tag) HLA-DRB4 Protein (Myc-DYKDDDDK Tag) (ABIN2722842)

HLA-DRB4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

HLA-DRB4 Proteins by Origin

Find HLA-DRB4 Proteins for a variety of species such as anti-Human HLA-DRB4. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-DRB4 Proteins by Source

Here you will find HLA-DRB4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HLA-DRB4 Proteins by Protein Type

Here you can find HLA-DRB4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

HLA-DRB4 Proteins by Application

Find HLA-DRB4 Proteins validated for a specific application such as AP, AA, AbP, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HLA-DRB4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306767
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2722842
Quantity 20 μg
Datasheet Datasheet

Aliases for HLA-DRB4 Proteins

major histocompatibility complex, class II, DR beta 4 (HLA-DRB4) Proteins
DR-4 Proteins
DR4 Proteins
DRB4 Proteins
HLA-DR4B Proteins
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