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HLA-DRB3 Proteins

(Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].

recommended

HLA-DRB3 Protein (AA 1-266) (GST tag) (ABIN1306765)

HLA-DRB3 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB

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HLA-DRB3 Proteins by Origin

Find HLA-DRB3 Proteins for a variety of species such as anti-Human HLA-DRB3. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-DRB3 Proteins by Source

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HLA-DRB3 Proteins by Protein Type

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HLA-DRB3 Proteins by Application

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Popular HLA-DRB3 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

HLA-DRB3 Protein (AA 1-266) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1306765

Quantity 10 μg

Datasheet Datasheet

Aliases for HLA-DRB3 Proteins

major histocompatibility complex, class II, DR beta 3 (HLA-DRB3) Proteins
major histocompatibility complex, class II, DRB3 (BOLA-DRB3) Proteins
BLA-DRB3 Proteins
Bota-DRB01 Proteins
Bota-DRB02 Proteins
Bota-DRB04 Proteins
Bota-DRB07 Proteins
Bota-DRB21 Proteins
Bota-DRB22 Proteins
HLA-DR3B Proteins
LA-DRB Proteins

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