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HLA-DRB1 Proteins

(Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].

recommended

HLA-DRB1 Protein (AA 30-227) (His tag) (ABIN5853579)

HLA-DRB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS

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recommended

HLA-DRB1 Protein (ABIN2129737)

HLA-DRB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % pure SDS

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recommended

HLA-DRB1 Protein (AA 27-264) (His tag) (ABIN7412938)

HLA-DRB1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % SDS, Imm, PC, WB

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HLA-DRB1 Proteins by Origin

Find HLA-DRB1 Proteins for a variety of species such as anti-Human HLA-DRB1, anti-Dog HLA-DRB1, anti-Mouse HLA-DRB1. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-DRB1 Proteins by Source

Here you will find HLA-DRB1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HLA-DRB1 Proteins by Protein Type

Here you can find HLA-DRB1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

HLA-DRB1 Proteins by Application

Find HLA-DRB1 Proteins validated for a specific application such as SDS, Imm, PC, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HLA-DRB1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

HLA-DRB1 Protein (AA 30-227) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5853579

Quantity 100 μg

Datasheet Datasheet

HLA-DRB1 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2129737

Quantity 100 μg

Datasheet Datasheet

HLA-DRB1 Protein (AA 27-264) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7412938

Quantity 100 μg

Datasheet Datasheet

HLA-DRB1 Protein (AA 30-266) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7412935

Quantity 100 μg

Datasheet Datasheet

HLA-DRB1 Protein (AA 30-227) (His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN6388240

Quantity 50 μg

Datasheet Datasheet

HLA-DRB1 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2722844

Quantity 20 μg

Datasheet Datasheet

HLA-DRB1 Protein (AA 30-227) (His tag)

Reactivity Dog

Source Yeast

Validations

Cat. No. ABIN1660811

Quantity 1 mg

Datasheet Datasheet

Aliases for HLA-DRB1 Proteins

major histocompatibility complex, class II, DR beta 1 (hla-drb1) Proteins
major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) Proteins
DRB1 Proteins
DRw10 Proteins
HLA-DR1B Proteins
HLA-DRB Proteins
MGC108235 Proteins
SS1 Proteins

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HLA-DRB1 Proteins by Origin

HLA-DRB1 Proteins by Source

HLA-DRB1 Proteins by Protein Type

HLA-DRB1 Proteins by Application

Popular HLA-DRB1 Proteins

Aliases for HLA-DRB1 Proteins

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