HLA-DPA1 Products
(Major Histocompatibility Complex, Class II, DP alpha 1 (HLA-DPA1))
Categories
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008].
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Featured HLA-DPA1 Categories
HLA-DPA1 Antibodies
High quality antibodies with extensive validation data.
HLA-DPA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HLA-DPA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN516495
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN516493
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC, IHC (fro)
Validations
- (3)
Cat. No.
ABIN2855822
Quantity
100 μL
Datasheet
Datasheet
Recommended HLA-DPA1 Proteins
Latest Publications for our HLA-DPA1 products
: "Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer." in: Cancer research and treatment : official journal of Korean Cancer Association, (2018) (PubMed).: "Gain in brain immunity in the oldest-old differentiates cognitively normal from demented individuals." in: PLoS ONE, Vol. 4, Issue 10, pp. e7642, (2009) (PubMed).
Synonyms and alternative names related to HLA-DPA1
major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1), DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1Protein level used designations for HLA-DPA1
- HLA class II histocompatibility antigen, DP alpha 1 chain
- HLA-SB alpha chain
- MHC class II DP3-alpha
- MHC class II HLA-DPA1 antigen
- MHC class II antigen
- Primed lymphocyte test-1
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