HLA-DMA Products
(Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
Categories
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008].
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Featured HLA-DMA Categories
HLA-DMA Antibodies
High quality antibodies with extensive validation data.
HLA-DMA ELISA Kits
Reliable ELISA kits for a wide range of species.
HLA-DMA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HLA-DMA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (6)
Cat. No.
ABIN516471
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN561267
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN2856977
Quantity
100 μL
Datasheet
Datasheet
Recommended HLA-DMA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5591923
Quantity
96 tests
Datasheet
Datasheet
Recommended HLA-DMA Proteins
Latest Publications for our HLA-DMA products
: "Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3." in: Biochemical and biophysical research communications, Vol. 235, Issue 1, pp. 185-90, (1997) (PubMed).: "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to chromosome 21q22.3." in: Human genetics, Vol. 99, Issue 5, pp. 616-23, (1997) (PubMed).
Synonyms and alternative names related to HLA-DMA
RT1 class II, locus DMa (RT1-DMa), SLA-DM alpha chain (SLA-DMA), major histocompatibility complex, class II, DM alpha (DLA-DMA), histocompatibility 2, class II, locus DMa (H2-DMa), major histocompatibility complex, class II, DM alpha (HLA-DMA), D6S222E, DMA, H-2Ma, H2-Ma, HLA-DMA, HLADM, RING6, RT1.DMa, RT1.MaProtein level used designations for HLA-DMA
- RT1 class II, DM alpha
- MHC class II-like alpha chain
- major histocompatibility complex, class II, DM alpha
- H2-M alpha
- class II histocompatibility antigen, M alpha chain
- histocompatibility 2, class II, locus Ma
- HLA class II histocompatibility antigen, DM alpha chain
- MHC class II antigen DMA
- really interesting new gene 6 protein
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