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Histone Cluster 2, H3c Products

(Histone Cluster 2, H3c (HIST2H3C))

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.

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Recommended Histone Cluster 2, H3c Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, IHC, WB, ICC
Validations
  • (5)
Cat. No. ABIN5542709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IHC, WB, IF/ICC
Validations
Cat. No. ABIN5943337
Quantity 100 μL
Datasheet Datasheet

Recommended Histone Cluster 2, H3c Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306712
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Histone Cluster 2, H3c products

Seward, Cubberley, Kim, Schonewald, Zhang, Tripet, Bentley: "Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins." in: Nature structural & molecular biology, Vol. 14, Issue 3, pp. 240-2, (2007) (PubMed).

Vakoc, Mandat, Olenchock, Blobel: "Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin." in: Molecular cell, Vol. 19, Issue 3, pp. 381-91, (2005) (PubMed).

Synonyms and alternative names related to Histone Cluster 2, H3c

histone cluster 2 H3 family member c (HIST2H3C), H3, H3.2, H3/M, H3F2, H3FM, H3FN

Protein level used designations for Histone Cluster 2, H3c

  • H3 histone family, member M
  • H3 histone, family 2
  • histone 2, H3c
  • histone H3.2
  • histone H3/m
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