HIST1H3E Products
(Histone Cluster 1, H3e (HIST1H3E))
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].
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Latest Publications for our HIST1H3E products
: "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment." in: Genes & development, Vol. 19, Issue 4, pp. 472-88, (2005) (PubMed).: "Arsenite induces prominent mitotic arrest via inhibition of G2 checkpoint activation in CGL-2 cells." in: Carcinogenesis, Vol. 26, Issue 1, pp. 53-63, (2004) (PubMed).
Synonyms and alternative names related to HIST1H3E
histone cluster 1 H3 family member e (HIST1H3E), histone cluster 1, H3e (Hist1h3e), H3-f, H3.1, H3/d, H3FDProtein level used designations for HIST1H3E
- H3 histone family, member D
- histone 1, H3e
- histone H3.1
- histone H3/d
- histone H3.2
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