High Mobility Group AT-Hook 1 Products
(High Mobility Group AT-Hook 1 (HMGA1))
Categories
This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured High Mobility Group AT-Hook 1 Categories
High Mobility Group AT-Hook 1 Antibodies
High quality antibodies with extensive validation data.
High Mobility Group AT-Hook 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
High Mobility Group AT-Hook 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended High Mobility Group AT-Hook 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ChIP
Validations
- (7)
Cat. No.
ABIN7267646
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN653050
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN736626
Quantity
100 μL
Datasheet
Datasheet
Recommended High Mobility Group AT-Hook 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967399
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956531
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956530
Quantity
96 tests
Datasheet
Datasheet
Recommended High Mobility Group AT-Hook 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1306792
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123326
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306793
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our High Mobility Group AT-Hook 1 products
: "Extranuclear Translocation of High-Mobility Group A1 Reduces the Invasion of Extravillous Trophoblasts Involved in the Pathogenesis of Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697250, (2017) (PubMed).: "Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1." in: International journal of oncology, Vol. 46, Issue 6, pp. 2526-34, (2015) (PubMed).
: "Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer." in: PLoS ONE, Vol. 9, Issue 5, pp. e98037, (2014) (PubMed).
: "Knockdown of HMGA1 inhibits human breast cancer cell growth and metastasis in immunodeficient mice." in: Biochemical and biophysical research communications, Vol. 434, Issue 1, pp. 70-4, (2013) (PubMed).
: "Overexpression of HMGA1 deregulates tumor growth via cdc25A and alters migration/invasion through a cdc25A-independent pathway in medulloblastoma." in: Acta neuropathologica, Vol. 123, Issue 4, pp. 553-71, (2012) (PubMed).
: "Differential expression and prognostic value of HMGA1 in pancreatic head and periampullary cancer." in: European journal of cancer (Oxford, England : 1990), Vol. 46, Issue 18, pp. 3393-9, (2010) (PubMed).
: "High mobility group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma." in: Cancer, Vol. 113, Issue 2, pp. 302-14, (2008) (PubMed).
: "HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 22, pp. 7637-44, (2004) (PubMed).
Synonyms and alternative names related to High Mobility Group AT-Hook 1
high mobility group AT-hook 1 (HMGA1), high mobility group AT-hook 1 (Hmga1), high mobility group protein HMG-I/HMG-Y (TSC_c24220), high mobility group AT-hook 1a (hmga1a), high mobility group protein HMG-I/HMG-Y (LOC705105), high mobility group AT-hook 1b (hmga1b), AL023995, HMG-I(Y), HMG-R, HMG-Y, hmga1, HMGA1, HMGA1A, Hmga1a, Hmga1b, Hmgi, HMGIY, Hmgiy, hmgiy, Hmgy, wu:fb12b06, wu:fb18f11, wu:fc19f01, wu:fi38b05, zgc:85677, zgc:153948Protein level used designations for High Mobility Group AT-Hook 1
- HMG-I(Y)
- high mobility group protein A1
- high mobility group protein HMG-I/HMG-Y
- high mobility group protein R
- high-mobility group (nonhistone chromosomal) protein isoforms I and Y
- nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y
- high mobility group AT-hook protein 1
- high-mobility group AT-hook 1
- high mobility group AT-hook 1
- high mobility group HMGA1A
- high mobility group HMGA1B
- non-histone protein
- high mobility group protein I
- High mobility group AT-hook protein 1
- High mobility group protein A1
- high mobility group-I protein
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