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HIF3A Products

(Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Categories

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011].

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Featured HIF3A Categories

HIF3A Antibodies

High quality antibodies with extensive validation data.

HIF3A ELISA Kits

Reliable ELISA kits for a wide range of species.

HIF3A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HIF3A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7074273
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN214599
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7156033
Quantity 100 μg
Datasheet Datasheet

Recommended HIF3A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956650
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6225197
Quantity 96 tests
Datasheet Datasheet

Recommended HIF3A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306624
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092935
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134893
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HIF3A products

Cuomo, Coppola, Botti, Maione, Forte, Scisciola, Liguori, Caiafa, Ursini, Galderisi, Cipollaro, Altucci, Cobellis: "Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells." in: Scientific reports, Vol. 8, Issue 1, pp. 5842, (2018) (PubMed).

Liu, Fang, Song, Jiang, He, Liu: "Expression of hypoxia-inducible factor 3α in hepatocellular carcinoma and its association with other hypoxia-inducible factors." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2470-2476, (2016) (PubMed).

Heyboer, Milovanova, Wojcik, Grant, Chin, Hardy, Lambert, Logue, Thom: "CD34+/CD45-dim stem cell mobilization by hyperbaric oxygen - changes with oxygen dosage." in: Stem cell research, Vol. 12, Issue 3, pp. 638-45, (2014) (PubMed).

Huang, Kapere Ochieng, Kempen, Munck, Swagemakers, van Ijcken, Grosveld, Tibboel, Rottier: "Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development." in: PLoS ONE, Vol. 8, Issue 2, pp. e57695, (2013) (PubMed).

Ando, Natsume, Iwami, Ohka, Kuchimaru, Kizaka-Kondoh, Ito, Saito, Sugita, Hoshino, Wakabayashi: "A hypoxia-inducible factor (HIF)-3α splicing variant, HIF-3α4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α4." in: Biochemical and biophysical research communications, Vol. 433, Issue 1, pp. 139-44, (2013) (PubMed).

Storti, Bolzoni, Donofrio, Airoldi, Guasco, Toscani, Martella, Lazzaretti, Mancini, Agnelli, Patrene, Maïga, Franceschi, Colla, Anderson, Neri, Amiot, Aversa, Roodman, Giuliani: "Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction." in: Leukemia, Vol. 27, Issue 8, pp. 1697-706, (2013) (PubMed).

Jackson, Zhang, Hadley, Rabbani, Zhang, Marks, Vujaskovic: "Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung." in: Free radical biology & medicine, Vol. 53, Issue 2, pp. 337-46, (2012) (PubMed).

Liu, DU, Huang, Luo, Wu, Chen: "[Mortality analyses for rungsten miners.]" in: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, Vol. 26, Issue 1, pp. 24-8, (2008) (PubMed).

Forooghian, Razavi, Timms: "Hypoxia-inducible factor expression in human RPE cells." in: The British journal of ophthalmology, Vol. 91, Issue 10, pp. 1406-10, (2007) (PubMed).

Wade, Guttentag, Gonzales, Maschhoff, Gonzales, Kolla, Singhal, Ballard: "Gene induction during differentiation of human pulmonary type II cells in vitro." in: American journal of respiratory cell and molecular biology, Vol. 34, Issue 6, pp. 727-37, (2006) (PubMed).

Synonyms and alternative names related to HIF3A

hypoxia inducible factor 3 alpha subunit (HIF3A), hypoxia inducible factor 3, alpha subunit (Hif3a), bHLHe17, HIF-3A, HIF3A, IPAS, Ipas, MOP7, Mop7, NEPAS, PASD7

Protein level used designations for HIF3A

  • HIF3-alpha-1
  • PAS domain-containing protein 7
  • basic-helix-loop-helix-PAS protein MOP7
  • class E basic helix-loop-helix protein 17
  • hypoxia-inducible factor 3-alpha
  • inhibitory PAS domain protein
  • member of PAS protein 7
  • HIF-3-alpha
  • HIF3-alpha
  • hypoxia inducible factor three alpha
  • neonatal and embryonic PAS
  • HIF-3 alpha
  • HIF3 alpha 1
  • hypoxia inducible factor 3 alpha
  • hypoxia inducible factor 3a
  • hypoxia-inducible factor 3 alpha
  • hypoxia inducible factor 3, alpha subunit
  • hypoxia-inducible factor-3 alpha
  • hypoxia-inducible factor 3-alpha-like
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