HGS Products
(Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
Categories
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010].
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Featured HGS Categories
HGS Antibodies
High quality antibodies with extensive validation data.
HGS ELISA Kits
Reliable ELISA kits for a wide range of species.
HGS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HGS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (1)
- (6)
Cat. No.
ABIN563958
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (6)
Cat. No.
ABIN2855140
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6262232
Quantity
100 μL
Datasheet
Datasheet
Recommended HGS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967366
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381201
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1136435
Quantity
96 tests
Datasheet
Datasheet
Recommended HGS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306594
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306592
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7502519
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HGS products
: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).: "The multivesicular body is the major internal site of prion conversion." in: Journal of cell science, Vol. 128, Issue 7, pp. 1434-43, (2015) (PubMed).
: "CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies." in: Molecular biology of the cell, Vol. 23, Issue 18, pp. 3602-11, (2012) (PubMed).
: "Endosomal clathrin drives actin accumulation at the immunological synapse. ..." in: Journal of cell science, Vol. 124, Issue Pt 5, pp. 820-30, (2011) (PubMed).
: "The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7R? surface expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 10, pp. 5051-61, (2011) (PubMed).
: "T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7535-47, (2011) (PubMed).
: "Proteolytic processing of protocadherin proteins requires endocytosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 41, pp. 17774-9, (2010) (PubMed).
: "GRIF1 binds Hrs and is a new regulator of endosomal trafficking." in: Journal of cell science, Vol. 119, Issue Pt 22, pp. 4689-701, (2006) (PubMed).
: "Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2." in: The Journal of biological chemistry, Vol. 280, Issue 11, pp. 10468-77, (2005) (PubMed).
: "A role for Hrs in endosomal sorting of ligand-stimulated and unstimulated epidermal growth factor receptor." in: Experimental cell research, Vol. 297, Issue 2, pp. 380-91, (2004) (PubMed).
Synonyms and alternative names related to HGS
hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs), hepatocyte growth factor-regulated tyrosine kinase substrate (hgs), HGF-regulated tyrosine kinase substrate (Hgs), Hepatocyte growth factor regulated tyrosine kinase substrate (Hrs), hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog (hgs.L), CG2903, Dmel\\CG2903, fi34f05, Hgr, hgs, HRS, Hrs, hrs, HRS-2, l(2)23AB5, l(2)23Ad, l(2)23Ad(Hrs), Vps27, vps27, wu:fi34f05, ZFYVE8, zgc:63492Protein level used designations for HGS
- human growth factor-regulated tyrosine kinase substrate
- protein pp110
- HGF-regulated tyrosine kinase substrate
- SNAP-25-interacting protein Hrs-2
- hepatocyte growth factor-regulated tyrosine kinase substrate
- CG2903-PA
- CG2903-PB
- CG2903-PC
- Hrs-PA
- Hrs-PB
- Hrs-PC
- hepatocyte growth factor regulated tyrosine kinase
- hepatocyte growth factor regulated tyrosine kinase substrate
- hepatocyte growth-factor-regulated substrate
- hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog
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