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HGF Proteins

(Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

recommended

HGF Protein (AA 32-728) (His tag) (ABIN7274808)

HGF Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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recommended

HGF Protein (AA 32-728) (Fc Tag) (ABIN7274810)

HGF Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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recommended

HGF Protein (AA 32-494, AA 495-728) (ABIN2017955)

HGF Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active

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HGF Proteins by Origin

Find HGF Proteins for a variety of species such as anti-Human HGF, anti-Rat HGF, anti-Mouse HGF. The species listed below are among those available. Click on a link to go to the corresponding products.

HGF Proteins by Source

Here you will find HGF Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HGF Proteins by Protein Type

Here you can find HGF Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

HGF Proteins by Application

Find HGF Proteins validated for a specific application such as SDS, WB, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

HGF Proteins by Biological Activity

Find HGF Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular HGF Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

HGF Protein (AA 32-728) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7274808

Quantity 100 μg

Datasheet Datasheet

HGF Protein (AA 32-728) (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7274810

Quantity 100 μg

Datasheet Datasheet

HGF Protein (AA 32-494, AA 495-728)

Reactivity Human

Source CHO Cells

Validations

Cat. No. ABIN2017955

Quantity 50 μg

Datasheet Datasheet

HGF Protein (Heterodimer)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN1589618

Quantity 5 μg

Datasheet Datasheet

HGF Protein (AA 496-728) (His-IF2DI Tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123306

Quantity 50 μg

Datasheet Datasheet

HGF Protein (AA 493-721) (His-IF2DI Tag)

Reactivity Chicken

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123304

Quantity 50 μg

Datasheet Datasheet

HGF Protein (AA 619-728) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1306590

Quantity 10 μg

Datasheet Datasheet

HGF Protein (AA 32-124) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1306589

Quantity 25 μg

Datasheet Datasheet

HGF Protein (AA 32-728) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7013376

Quantity 100 μg

Datasheet Datasheet

HGF Protein (AA 32-728) (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN6992334

Quantity 100 μg

Datasheet Datasheet

HGF Protein (AA 477-728) (GST tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1047161

Quantity 100 μg

Datasheet Datasheet

HGF Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2722630

Quantity 20 μg

Datasheet Datasheet

HGF Protein

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN2745697

Quantity 5 μg

Datasheet Datasheet

HGF Protein

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN935435

Quantity 5 μg

Datasheet Datasheet

HGF Protein (AA 33-728) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7505740

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our HGF Proteins

Ding, You, Tian, Gu, Deng: "Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation." in: International journal of biological sciences, Vol. 16, Issue 14, pp. 2595-2611, (2020) (PubMed).

Leung, Xue, Wang, Rougerie, Sharma, Eddy, Cox, Condeelis: "Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway." in: Oncogene, (2016) (PubMed).

Rezzola, Dal Monte, Belleri, Bugatti, Chiodelli, Corsini, Cammalleri, Cancarini, Morbidelli, Oreste, Bagnoli, Semeraro, Presta: "Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy." in: Diabetes, Vol. 64, Issue 7, pp. 2581-92, (2015) (PubMed).

Lohr, Mock, Beckhove, Herold-Mende: "Endothelial Cells Derived from Non-malignant Tissues Are of Limited Value as Models for Brain Tumor Vasculature." in: Anticancer research, Vol. 35, Issue 5, pp. 2681-90, (2015) (PubMed).

Ueda, Ito, Shiraishi, Taniguchi, Kayukawa, Nakanishi, Nakamura, Naya, Hongo, Kamoi, Okihara, Kawauchi, Miki: "PAX2 promoted prostate cancer cell invasion through transcriptional regulation of HGF in an in vitro model." in: Biochimica et biophysica acta, Vol. 1852, Issue 11, pp. 2467-73, (2015) (PubMed).

Musiani, Konda, Pavan, Torchiaro, Sassi, Noghero, Erriquez, Perera, Olivero, Di Renzo: "Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 9, pp. 4055-67, (2015) (PubMed).

Okajima, Miyazawa, Kitamura: "Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury." in: European journal of biochemistry / FEBS, Vol. 193, Issue 2, pp. 375-81, (1990) (PubMed).

Tashiro, Hagiya, Nishizawa, Seki, Shimonishi, Shimizu, Nakamura: "Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 8, pp. 3200-4, (1990) (PubMed).

Aliases for HGF Proteins

hepatocyte growth factor (HGF) Proteins
hepatocyte growth factor (Hgf) Proteins
C230052L06Rik Proteins
DFNB39 Proteins
F-TCF Proteins
HGF Proteins
HGF/SF Proteins
HGFB Proteins
HPTA Proteins
NK1 Proteins
NK2 Proteins
SF Proteins
SF/HGF Proteins

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HGF Proteins by Origin

HGF Proteins by Source

HGF Proteins by Protein Type

HGF Proteins by Application

HGF Proteins by Biological Activity

Popular HGF Proteins

Latest Publications for our HGF Proteins

Aliases for HGF Proteins

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