HGF Products
(Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
Categories
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured HGF Categories
HGF Antibodies
High quality antibodies with extensive validation data.
HGF ELISA Kits
Reliable ELISA kits for a wide range of species.
HGF Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HGF Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (1)
- (5)
Cat. No.
ABIN516424
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (5)
- (8)
Cat. No.
ABIN2781816
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (2)
- (3)
Cat. No.
ABIN388462
Quantity
400 μL
Datasheet
Datasheet
Recommended HGF ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (9)
- (1)
Cat. No.
ABIN6956494
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956495
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
Cat. No.
ABIN6956496
Quantity
96 tests
Datasheet
Datasheet
Recommended HGF Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274808
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274810
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
CHO Cells
Validations
- (2)
Cat. No.
ABIN2017955
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our HGF products
: "Scalable production of tissue-like vascularized liver organoids from human PSCs. ..." in: Experimental & molecular medicine, Vol. 55, Issue 9, pp. 2005-2024, (2023) (PubMed).: "Angiocrine Hepatocyte Growth Factor Signaling Controls Physiological Organ and Body Size and Dynamic Hepatocyte Proliferation to Prevent Liver Damage during Regeneration." in: The American journal of pathology, Vol. 190, Issue 2, pp. 358-371, (2020) (PubMed).
: "Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation." in: International journal of biological sciences, Vol. 16, Issue 14, pp. 2595-2611, (2020) (PubMed).
: "Evaluation of liver function by means of serum cytokeratin 18 and hepatocyte growth factor levels in patients with obstructive jaundice." in: Acta chirurgica Belgica, Vol. 118, Issue 3, pp. 167-171, (2019) (PubMed).
: "Portal vein stenosis preconditioning of living donor liver in swine: early mechanisms of liver regeneration and gain of hepatic functional mass." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 315, Issue 1, pp. G117-G125, (2019) (PubMed).
: "What is the Best Degree of Hyaluronic Acid Crosslinking in Increasing Growth Factors Level of Platelet-Rich Fibrin Lysate?" in: Journal of stem cells & regenerative medicine, Vol. 15, Issue 1, pp. 3-7, (2019) (PubMed).
: "Inherent control of hepatocyte proliferation after subtotal liver resection." in: Cell biology international, (2019) (PubMed).
: "Interleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model." in: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 22, (2019) (PubMed).
: "Overexpression of c-Met in bone marrow mesenchymal stem cells improves their effectiveness in homing and repair of acute liver failure." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 162, (2018) (PubMed).
: "Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR-γ and subsequent expression of HGF in colons." in: Toxicology and applied pharmacology, Vol. 343, pp. 1-15, (2018) (PubMed).
Synonyms and alternative names related to HGF
hepatocyte growth factor (HGF), hepatocyte growth factor (Hgf), C230052L06Rik, DFNB39, F-TCF, HGF, HGF/SF, HGFB, HPTA, NK1, NK2, SF, SF/HGFProtein level used designations for HGF
- fibroblast-derived tumor cytotoxic factor
- hepatocyte growth factor
- hepatopoeitin-A
- hepatopoietin-A
- lung fibroblast-derived mitogen
- SF
- scatter factor
- hepapoietin A
- HGF alpha-chain
- hepatocyte growth factor /scatter factor
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