HERV-FRD Provirus Ancestral Env Polyprotein Products
(HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd))
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Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of a endogenous retrovirus provirus on rat chromosome 12 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Apr 2015].
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Featured HERV-FRD Provirus Ancestral Env Polyprotein Categories
HERV-FRD Provirus Ancestral Env Polyprotein Antibodies
High quality antibodies with extensive validation data.
HERV-FRD Provirus Ancestral Env Polyprotein Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HERV-FRD Provirus Ancestral Env Polyprotein Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7171184
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7171183
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
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Cat. No.
ABIN656942
Quantity
400 μL
Datasheet
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Recommended HERV-FRD Provirus Ancestral Env Polyprotein Proteins
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Reactivity
Source
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Cat. No.
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Reactivity
Human
Source
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Validations
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Cat. No.
ABIN1353102
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our HERV-FRD Provirus Ancestral Env Polyprotein products
: "Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2." in: Cell adhesion & migration, Vol. 10, Issue 1-2, pp. 39-55, (2017) (PubMed).: "PLAC1 is involved in human trophoblast syncytialization." in: Reproductive biology, Vol. 16, Issue 3, pp. 218-224, (2017) (PubMed).
: "Involvement of nephrin in human placental trophoblast syncytialization." in: Reproduction (Cambridge, England), Vol. 149, Issue 4, pp. 339-46, (2015) (PubMed).
: "Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 81, (2015) (PubMed).
: "Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta." in: Retrovirology, Vol. 5, pp. 6, (2008) (PubMed).
Synonyms and alternative names related to HERV-FRD Provirus Ancestral Env Polyprotein
endogenous retrovirus group FRD member 1, envelope (ERVFRD-1), endogenous retrovirus group FRD member 1, envelope (Ervfrd-1), envFRD, ERVFRDE1, GLLL6191, Gm52, HERV-FRD, HERV-W/FRD, Syna, UNQ6191Protein level used designations for HERV-FRD Provirus Ancestral Env Polyprotein
- HERV-FRD provirus ancestral Env polyprotein
- HERV-FRD_6p24.1 provirus ancestral Env polyprotein
- endogenous retrovirus group FRD member 1
- envelope polyprotein
- syncytin 2
- envelope glycoprotein syncytin-A
- syncytin a
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