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HERV-FRD Provirus Ancestral Env Polyprotein Products

(HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd))
Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of a endogenous retrovirus provirus on rat chromosome 12 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Apr 2015].

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Featured HERV-FRD Provirus Ancestral Env Polyprotein Categories

HERV-FRD Provirus Ancestral Env Polyprotein Antibodies

High quality antibodies with extensive validation data.

HERV-FRD Provirus Ancestral Env Polyprotein Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our HERV-FRD Provirus Ancestral Env Polyprotein products

Cui, Wang, Lu, Wang, Zheng, Li, Yang, Jia, Zhao, Wang, Wang, Wang, Zhu, Lin, Wang: "Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2." in: Cell adhesion & migration, Vol. 10, Issue 1-2, pp. 39-55, (2017) (PubMed).

Chang, Wang, Cui, Peng, Fan, Xue, Yang: "PLAC1 is involved in human trophoblast syncytialization." in: Reproductive biology, Vol. 16, Issue 3, pp. 218-224, (2017) (PubMed).

Li, Zheng, Wang, Lu, Zhu, Lin, Wang, Yu, Fu: "Involvement of nephrin in human placental trophoblast syncytialization." in: Reproduction (Cambridge, England), Vol. 149, Issue 4, pp. 339-46, (2015) (PubMed).

Díaz-Carballo, Acikelli, Klein, Jastrow, Dammann, Wyganowski, Guemues, Gustmann, Bardenheuer, Malak, Tefett, Khosrawipour, Giger-Pabst, Tannapfel, Strumberg: "Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 81, (2015) (PubMed).

Malassiné, Frendo, Blaise, Handschuh, Gerbaud, Tsatsaris, Heidmann, Evain-Brion: "Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta." in: Retrovirology, Vol. 5, pp. 6, (2008) (PubMed).

Synonyms and alternative names related to HERV-FRD Provirus Ancestral Env Polyprotein

endogenous retrovirus group FRD member 1, envelope (ERVFRD-1), endogenous retrovirus group FRD member 1, envelope (Ervfrd-1), envFRD, ERVFRDE1, GLLL6191, Gm52, HERV-FRD, HERV-W/FRD, Syna, UNQ6191

Protein level used designations for HERV-FRD Provirus Ancestral Env Polyprotein

  • HERV-FRD provirus ancestral Env polyprotein
  • HERV-FRD_6p24.1 provirus ancestral Env polyprotein
  • endogenous retrovirus group FRD member 1
  • envelope polyprotein
  • syncytin 2
  • envelope glycoprotein syncytin-A
  • syncytin a
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