HERPUD1 Products
(Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))
Categories
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013].
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Featured HERPUD1 Categories
HERPUD1 Antibodies
High quality antibodies with extensive validation data.
HERPUD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HERPUD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HERPUD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IP
Validations
- (3)
- (6)
Cat. No.
ABIN564201
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6262218
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN564200
Quantity
100 μg
Datasheet
Datasheet
Recommended HERPUD1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967460
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1137502
Quantity
96 tests
Datasheet
Datasheet
Recommended HERPUD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123358
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306541
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306538
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our HERPUD1 products
: "Radioprotective effects of genistein on HL-7702 cells via the inhibition of apoptosis and DNA damage." in: Cancer letters, Vol. 366, Issue 1, pp. 100-11, (2015) (PubMed).: "BRSK2 is regulated by ER stress in protein level and involved in ER stress-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 423, Issue 4, pp. 813-8, (2012) (PubMed).
: "Decreased ER-associated degradation of alpha-TCR induced by Grp78 depletion with the SubAB cytotoxin." in: The international journal of biochemistry & cell biology, Vol. 40, Issue 12, pp. 2865-79, (2008) (PubMed).
: "Apoptosis induction of 2'-hydroxycinnamaldehyde as a proteasome inhibitor is associated with ER stress and mitochondrial perturbation in cancer cells." in: Biochemical pharmacology, Vol. 74, Issue 4, pp. 557-65, (2007) (PubMed).
Synonyms and alternative names related to HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog (herpud1.S), homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog (herpud1.L), homocysteine inducible ER protein with ubiquitin like domain 1 (herpud1), homocysteine inducible ER protein with ubiquitin like domain 1 (HERPUD1), homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 (herpud1), homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 (Herpud1), homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), herp, HERP, Herp, herpud1, HERPUD1, herpud1-a, mif1, Mif1, Mifl, sup, SUP, Sup, zgc:114134Protein level used designations for HERPUD1
- homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
- MMS-inducible
- homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein
- methyl methanesulfonate (MMF)-inducible fragment protein 1
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