HERC5 Products
(Hect Domain and RLD 5 (HERC5))
Categories
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq, Jul 2008].
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Featured HERC5 Categories
HERC5 Antibodies
High quality antibodies with extensive validation data.
HERC5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HERC5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Horse, Human, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN2774739
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7150946
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN565561
Quantity
50 μL
Datasheet
Datasheet
Recommended HERC5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210279
Quantity
96 tests
Datasheet
Datasheet
Recommended HERC5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123283
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306534
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2129673
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HERC5 products
: "Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin." in: Open biology, Vol. 6, Issue 8, (2016) (PubMed).: "90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus." in: Neoplasia (New York, N.Y.), Vol. 18, Issue 10, pp. 618-625, (2016) (PubMed).
: "Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export." in: Retrovirology, Vol. 11, pp. 27, (2014) (PubMed).
: "Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag." in: Retrovirology, Vol. 8, pp. 95, (2011) (PubMed).
Synonyms and alternative names related to HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5), hect domain and RLD 5 (HERC5), CEB1, CEBP1, HERC5Protein level used designations for HERC5
- E3 ISG15--protein ligase HERC5
- hect domain and RLD 5
- probable E3 ubiquitin-protein ligase HERC5-like
- HECT domain and RCC1-like domain-containing protein 5
- cyclin-E-binding protein 1
- probable E3 ubiquitin-protein ligase HERC5
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