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(High Density Lipoprotein (HDL))
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The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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Featured HDL Categories
HDL Antibodies
High quality antibodies with extensive validation data.
HDL ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended HDL Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
Cat. No.
ABIN2175836
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN2175841
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN2175837
Quantity
100 μL
Datasheet
Datasheet
Recommended HDL ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963172
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956524
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956525
Quantity
96 tests
Datasheet
Datasheet
Recommended HDL Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Latest Publications for our HDL products
: "Perindopril ameliorates experimental Alzheimer's disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signaling." in: Inflammopharmacology, Vol. 28, Issue 5, pp. 1343-1364, (2020) (PubMed).: "Anthocyanin Cyanidin-3-Glucoside Attenuates Platelet Granule Release in Mice Fed High-Fat Diets." in: Journal of nutritional science and vitaminology, Vol. 63, Issue 4, pp. 237-243, (2018) (PubMed).
: "Endurance training selectively increases high-density lipoprotein-bound sphingosine-1-phosphate in the plasma." in: Scandinavian journal of medicine & science in sports, Vol. 28, Issue 1, pp. 57-64, (2018) (PubMed).
: "Inhibitory effects of sweet cherry anthocyanins on the obesity development in C57BL/6 mice." in: International journal of food sciences and nutrition, Vol. 65, Issue 3, pp. 351-9, (2014) (PubMed).
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