HDAC5 Products
(Histone Deacetylase 5 (HDAC5))
Categories
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured HDAC5 Categories
HDAC5 Antibodies
High quality antibodies with extensive validation data.
HDAC5 ELISA Kits
Reliable ELISA kits for a wide range of species.
HDAC5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HDAC5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (5)
Cat. No.
ABIN6262182
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN6255378
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6141675
Quantity
100 μL
Datasheet
Datasheet
Recommended HDAC5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6956576
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380596
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380178
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended HDAC5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306456
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407238
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092932
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our HDAC5 products
: "Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation." in: Cellular and molecular gastroenterology and hepatology, Vol. 12, Issue 4, pp. 1457-1477, (2022) (PubMed).: "Upregulated Expression of Intestinal Antimicrobial Peptide HD5 Associated with Renal Function in IgA Nephropathy." in: Disease markers, Vol. 2020, pp. 2078279, (2020) (PubMed).
: "Urinary antimicrobial peptides: Potential novel biomarkers of obstructive uropathy." in: Journal of pediatric urology, Vol. 14, Issue 3, pp. 238.e1-238.e6, (2018) (PubMed).
: "Evaluation of novel urinary tract infection biomarkers in children." in: Pediatric research, Vol. 79, Issue 6, pp. 934-9, (2016) (PubMed).
: "Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma." in: Anticancer research, Vol. 36, Issue 5, pp. 2527-34, (2016) (PubMed).
: "G9a inhibits MEF2C activity to control sarcomere assembly." in: Scientific reports, Vol. 6, pp. 34163, (2016) (PubMed).
: "AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 15, pp. 2520-36, (2015) (PubMed).
: "On birth single dose live attenuated OPV and BCG vaccination induces gut cathelicidin LL37 responses at 6 week of age: a natural experiment." in: Vaccine, Vol. 33, Issue 1, pp. 18-21, (2014) (PubMed).
: "The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 34181-9, (2013) (PubMed).
: "Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules." in: American journal of physiology. Heart and circulatory physiology, Vol. 300, Issue 6, pp. H2187-95, (2011) (PubMed).
Synonyms and alternative names related to HDAC5
histone deacetylase 5 (HDAC5), histone deacetylase 5 (Hdac5), histone deacetylase 5 (HDA05), histone deacetylase 5 (hdac5), AI426555, ATHDA5, HD5, HDA5, Hdac4, histone deacetylase 5, MAF19.7, MAF19_7, mHDA1, mKIAA0600, NY-CO-9Protein level used designations for HDAC5
- antigen NY-CO-9
- HD5
- histone deacetylase 4
- histone deacetylase mHDA1
- histone deacetylase 5
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