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HDAC4/HDAC5/HDAC9 Antibodies

(HDAC4,HDAC5,HDAC9)
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

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Recommended HDAC4/HDAC5/HDAC9 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, ELISA
Validations
  • (3)
Cat. No. ABIN7138137
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7138509
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN319389
Quantity 0.1 mL
Datasheet Datasheet

Latest Publications for our HDAC4/HDAC5/HDAC9 products

Liu, Greer, Secombe: "KDM5 interacts with Foxo to modulate cellular levels of oxidative stress." in: PLoS genetics, Vol. 10, Issue 10, pp. e1004676, (2014) (PubMed).

Vigushin, Coombes: "Targeted histone deacetylase inhibition for cancer therapy." in: Current cancer drug targets, Vol. 4, Issue 2, pp. 205-18, (2004) (PubMed).

Thiagalingam, Cheng, Lee, Mineva, Thiagalingam, Ponte: "Histone deacetylases: unique players in shaping the epigenetic histone code." in: Annals of the New York Academy of Sciences, Vol. 983, pp. 84-100, (2003) (PubMed).

Marmorstein: "Structure and function of histone acetyltransferases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 5-6, pp. 693-703, (2001) (PubMed).

Synonyms and alternative names related to HDAC4/HDAC5/HDAC9

histone deacetylase 4 (HDAC4), AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA

Protein level used designations for HDAC4/HDAC5/HDAC9

  • histone deacetylase A
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