HDAC4 Products
(Histone Deacetylase 4 (HDAC4))
Categories
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
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Featured HDAC4 Categories
HDAC4 Antibodies
High quality antibodies with extensive validation data.
HDAC4 ELISA Kits
Reliable ELISA kits for a wide range of species.
HDAC4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HDAC4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7441235
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN5542325
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN523212
Quantity
100 μg
Datasheet
Datasheet
Recommended HDAC4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956574
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956575
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380595
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended HDAC4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1306452
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306454
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2722509
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our HDAC4 products
: "Sarcoplasmic reticulum Ca2+ -induced Ca2+ release regulates class IIa HDAC localization in mouse embryonic cardiomyocytes." in: Physiological reports, Vol. 6, Issue 2, (2019) (PubMed).: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." in: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).
: "HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder." in: Human molecular genetics, Vol. 25, Issue 18, pp. 3887-3907, (2016) (PubMed).
: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).
: "PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).
: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).
: "The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 34181-9, (2013) (PubMed).
: "Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity." in: PLoS ONE, Vol. 8, Issue 9, pp. e75342, (2013) (PubMed).
: "HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration." in: PLoS biology, Vol. 11, Issue 11, pp. e1001717, (2013) (PubMed).
: "Differential expression of mature microRNAs involved in muscle maintenance of hibernating little brown bats, Myotis lucifugus: a model of muscle atrophy resistance." in: Genomics, proteomics & bioinformatics, Vol. 10, Issue 5, pp. 295-301, (2012) (PubMed).
Synonyms and alternative names related to HDAC4
histone deacetylase 4 (PTRG_03699), hypothetical protein (PGTG_15512), Histone deacetylase 4 (HDAC4), GF18710 gene product from transcript GF18710-RC (Dana\GF18710), histone deacetylase 4 (HDAC4), histone deacetylase 4 (Hdac4), histone deacetylase 4 (hdac4), 4932408F19Rik, AHO3, AI047285, BDMR, CG1770, DanaGF18710, dana_GLEANR_19966, DHDAC4, dHDAC4, Dmel\\CG1770, dmHDA405, GC1770, GF18710, HA6116, HD4, HDAC, HDAC-4, HDAC-A, hdac4, HDAC4, HDAC4a, HDACA, wu:fa96d08, wu:fc56f08, zgc:152701Protein level used designations for HDAC4
- histone deacetylase 4
- CG1770-PB
- CG1770-PD
- CG1770-PE
- CG1770-PF
- CG1770-PG
- CG1770-PH
- CG1770-PI
- CG1770-PJ
- HDAC4-PB
- HDAC4-PD
- HDAC4-PE
- HDAC4-PF
- HDAC4-PG
- HDAC4-PH
- HDAC4-PI
- HDAC4-PJ
- DanaGF18710-PA
- DanaHDAC4-PA
- GF18710-PA
- HDAC4
- HDAC4-PA
- histone deacetylase A
- HD4
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