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HDAC3 Products

(Histone Deacetylase 3 (HDAC3))

Categories

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].

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Featured HDAC3 Categories

HDAC3 Antibodies

High quality antibodies with extensive validation data.

HDAC3 ELISA Kits

Reliable ELISA kits for a wide range of species.

HDAC3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HDAC3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IP, ChIP
Validations
  • (3)
  • (9)
Cat. No. ABIN3023018
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (6)
Cat. No. ABIN6262179
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (9)
Cat. No. ABIN6256332
Quantity 100 μL
Datasheet Datasheet

Recommended HDAC3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967438
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967437
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967436
Quantity 96 tests
Datasheet Datasheet

Recommended HDAC3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1306448
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306450
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7425037
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HDAC3 products

Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." in: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

Wei, Liu, Chen, Gao, Lu, Zhang, Ding, Wang, Chen, Shi, Li, Yu, Wong: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." in: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).

Tanaka, Muto, Shima, Katoh, Sax, Tajima, Brydun, Ikura, Yoshizawa, Masai, Hoshikawa, Noda, Nio, Ochiai, Igarashi: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." in: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, (2016) (PubMed).

Baek, Park, Rhim, Park, Kim, Kim, Nam: "Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma." in: Anticancer research, Vol. 36, Issue 5, pp. 2527-34, (2016) (PubMed).

Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

Liu, Lu, Zhang, Zhang, Lu, Xie, Cheng, Shen, Zhang: "C/EBPα negatively regulates SIRT7 expression via recruiting HDAC3 to the upstream-promoter of hepatocellular carcinoma cells." in: Biochimica et biophysica acta, Vol. 1859, Issue 2, pp. 348-54, (2016) (PubMed).

Rajendran, Dashwood, Li, Kang, Kim, Johnson, Fischer, Löhr, Williams, Ho, Yamamoto, Lieberman, Dashwood: "Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon." in: Clinical epigenetics, Vol. 7, pp. 102, (2015) (PubMed).

Jiang, Ye, Guo, Lu, Gao: "Inhibition of HDAC3 promotes ligand-independent PPAR? activation by protein acetylation." in: Journal of molecular endocrinology, Vol. 53, Issue 2, pp. 191-200, (2014) (PubMed).

Brodie, Li, El-Kommos, Kang, Ramalingam, Behera, Gandhi, Kowalski, Sica, Khuri, Vertino, Brandes: "Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 3, pp. 351-61, (2014) (PubMed).

Mano, Suzuki, Tsuji, Iwata: "Differential effect of HDAC3 on cytoplasmic and nuclear huntingtin aggregates." in: PLoS ONE, Vol. 9, Issue 11, pp. e111277, (2014) (PubMed).

Synonyms and alternative names related to HDAC3

Histone deacetylase 3 (HDAC3), histone deacetylase 3 (hdac3), histone deacetylase 3 (CNL05260), histone deacetylase 3 (HDAC3), histone deacetylase 3 (Hdac3), histone deacetylase 3 S homeolog (hdac3.S), AW537363, CG2128, DHDAC3, dHDAC3, Dmel\\CG2128, dmHDA402, DmHDAC3, Dromel_CG2128_FBtr0078767_hdac3_mORF, hd3, HD3, HDAC, HDAC3, Hdac 3, hdac3, HDm, RPD3, rpd3-2, RPD3-2, XRpd3, zgc:55927

Protein level used designations for HDAC3

  • CG2128-PA
  • Hdac3-PA
  • histone Deacetylase-3
  • histone deacetylase 3
  • SMAP45
  • HD3
  • HDAC3 splicing HDAC3alpha
  • HDAC3 splicing HDAC3beta
  • HDAC3 splicing HDAC3delta
  • HDAC3 splicing HDAC3gamma
  • histone deacetylase-3
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