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HDAC2 Products

(Histone Deacetylase 2 (HDAC2))

Categories

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].

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Featured HDAC2 Categories

HDAC2 Antibodies

High quality antibodies with extensive validation data.

HDAC2 ELISA Kits

Reliable ELISA kits for a wide range of species.

HDAC2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HDAC2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (6)
Cat. No. ABIN6242378
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN7267708
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (1)
  • (4)
Cat. No. ABIN653718
Quantity 400 μL
Datasheet Datasheet

Recommended HDAC2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
Cat. No. ABIN5526695
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962266
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967435
Quantity 96 tests
Datasheet Datasheet

Recommended HDAC2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123344
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Hi-5 Cells
Validations
  • (1)
Cat. No. ABIN667944
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412992
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HDAC2 products

Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." in: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

Du, Tang, Yuan: "Suppression of HDAC2 by sodium butyrate alleviates apoptosis of kidney cells in db/db mice and HG‑induced NRK‑52E cells." in: International journal of molecular medicine, Vol. 45, Issue 1, pp. 210-222, (2020) (PubMed).

Tang, Zhou, Xiang, Wu, Zhang, Wang, Liu, Zhang, Peng, Huang, Cai, Bai, Bai, Zhu, Gu, Xiong, Ye, Li, Liu, Wang: "The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer." in: Nature communications, Vol. 10, Issue 1, pp. 663, (2019) (PubMed).

Wu, Li, Qin, Cheng, Hao, Jin, Zhu: "Jinwei Tang modulates HDAC2 expression in a rat model of COPD." in: Experimental and therapeutic medicine, Vol. 15, Issue 3, pp. 2604-2610, (2018) (PubMed).

Wei, Liu, Chen, Gao, Lu, Zhang, Ding, Wang, Chen, Shi, Li, Yu, Wong: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." in: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).

Li, Liu, He, Yang, Pei, Li, Liu, Chen, Xie, Xu, Ting, Zhang, Jin, Liu, Zhang, Yuan, Yang, Wu, Zhang, Yang, Yi, Liang, Shang, Sun: "ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin." in: Nature communications, Vol. 8, Issue 1, pp. 691, (2018) (PubMed).

Guo, Bai, Zhao, Zhou, Shen, Yun, Zhang, Zhu, Wang: "Acetylation of 53BP1 dictates the DNA double strand break repair pathway." in: Nucleic acids research, Vol. 46, Issue 2, pp. 689-703, (2018) (PubMed).

Wei, Lu, Ma, Yu, Zhang, Xiong, Wang, Zhang, Fang, Wang: "Synergistic activity of imatinib and AR-42 against chronic myeloid leukemia cells mainly through HDAC1 inhibition." in: Life sciences, Vol. 211, pp. 224-237, (2018) (PubMed).

Leucker, Nomura, Kim, Bhatta, Wang, Wecker, Jandu, Santhanam, Berkowitz, Romer, Pandey: "Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6." in: American journal of physiology. Heart and circulatory physiology, Vol. 312, Issue 4, pp. H711-H720, (2017) (PubMed).

Sirchia, Faversani, Rovina, Russo, Paganini, Savi, Augello, Rosso, Del Gobbo, Tabano, Bosari, Miozzo: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." in: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).

Synonyms and alternative names related to HDAC2

histone deacetylase 2 (HDAC2), histone deacetylase 2 (Hdac2), histone deacetylase 2 S homeolog (hdac2.S), histone deacetylase 2 (HDA2), D10Wsu179e, HD2, HISTONE DEACETYLASE, histone deacetylase 2, mRPD3, RPD3, T1N24.9, T1N24_9, YAF1, Yy1bp

Protein level used designations for HDAC2

  • YY1-associated factor 1
  • transcriptional regulator homolog RPD3
  • HD2
  • YY1 transcription factor-binding protein
  • histone deacetylase-2
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