HCST Products
(Hematopoietic Cell Signal Transducer (HCST))
Categories
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured HCST Categories
HCST Antibodies
High quality antibodies with extensive validation data.
HCST ELISA Kits
Reliable ELISA kits for a wide range of species.
HCST Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HCST Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, FACS, IF (p), IF (cc), ELISA, IHC (fro), IHC (p), ICC
Validations
- (1)
Cat. No.
ABIN2175291
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN2175296
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, FACS, IF (p), IF (cc)
Validations
Cat. No.
ABIN5004329
Quantity
100 μL
Datasheet
Datasheet
Recommended HCST ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1136280
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1136281
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1136283
Quantity
96 tests
Datasheet
Datasheet
Recommended HCST Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7490759
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7281338
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2719205
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our HCST products
: "Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model." in: eLife, Vol. 10, (2021) (PubMed).: "NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells." in: Nature immunology, Vol. 7, Issue 5, pp. 524-32, (2006) (PubMed).
Synonyms and alternative names related to HCST
hematopoietic cell signal transducer (HCST), hematopoietic cell signal transducer (Hcst), hematopoietic cell signal transducer (hcst), hematopoietic cell signal transducer L homeolog (hcst.L), DAP10, Dap10, dap10, dap10-A, HCST, hcst, hcsta, KAP10, kap10, PIK3AP, pik3apProtein level used designations for HCST
- DNAX-activation protein 10
- kinase assoc pro of ~10kDa
- kinase assoc protein
- membrane protein DAP10
- phosphoinositide-3-kinase adaptor protein
- transmembrane adapter protein KAP10
- immunoreceptor DAP10
- hematopoietic cell signal transducer
- putative membrane adaptor molecule
- dap10
- hematopoietic cell signal transducer A
- hematopoietic cell signal transducer L homeolog
- signal subunit, signaling transmembrane co-receptor
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