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HCP Products

(Host Cell Proteins (HCP))

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In biopharmaceutic manufacturing the term host cell proteins (HCPs) clusters proteins impurities derived from the host organism which are present during in the manufacturing process of monoclonal antibodies, antibody-drug-conjugates, therapeutic proteins, and other protein-based biopharmaceuticals.

Quantitation and removal of HCPs in the final drug product to acceptable low levels is essential. Impurities accompanied with recombinant biotherapeutics can significantly affect drug efficacy and cause immunogenicity.

Custom HCP Antibody Services

Are you interested in a custom made antibody and assays tailored for your needs to screen your biological production process for HCP impurities? In that case we have the right program for you at hand.

Benefit from the combined expertise of antibodies-online and our partner Rockland Immunochemicals, Inc. (Rockland).. Leverage Rockland’s 15+ years of success generating custom polyclonal HCP antibodies to keep your biopharmaceutical development program meeting deadlines and moving efficiently.

Our comprehensive, fully customizable services cover all aspects of anti-HCP antibody generation, from antigen preparation and assay development to documentation and manufacturing.

Learn more about our Custom HCP Antibody Services

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Recommended HCP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN1113182
Quantity 100 μL
Datasheet Datasheet
Reactivity E. coli
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN1607604
Quantity 100 μL
Datasheet Datasheet
Reactivity Chinese Hamster
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN1113181
Quantity 100 μL
Datasheet Datasheet

Recommended HCP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chinese Hamster
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN7538037
Quantity 96 tests
Datasheet Datasheet
Reactivity Chinese Hamster
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN7538038
Quantity 96 tests
Datasheet Datasheet
Reactivity Pichia pastoris
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN7538041
Quantity 96 tests
Datasheet Datasheet

Recommended HCP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity E. coli
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN1607597
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our HCP products

Cunha, Stolet, Strauch, Pereira, Dumard, Gomes, Monteiro, Higa, Souza, Fonseca, Pontes, Meirelles, Albuquerque, Sacramento, Fintelman-Rodrigues, Lima, Alvim, Marsili, Caldeira, Zingali, de Oliveira et al.: "Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency. ..." in: iScience, Vol. 24, Issue 11, pp. 103315, (2021) (PubMed).

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