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HCN1 Products

(Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

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The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011].

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Featured HCN1 Categories

HCN1 Antibodies

High quality antibodies with extensive validation data.

HCN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HCN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, AA
Validations
  • (5)
Cat. No. ABIN361763
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, AA
Validations
  • (5)
Cat. No. ABIN2483966
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, AA
Validations
  • (5)
Cat. No. ABIN2483965
Quantity 100 μg
Datasheet Datasheet

Recommended HCN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210510
Quantity 96 tests
Datasheet Datasheet

Recommended HCN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123393
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3110457
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3132196
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HCN1 products

Zhou, Lin, Si, Ru, Chen, Xiao, Li: "Downregulation of HCN1 channels in hippocampus and prefrontal cortex in methamphetamine re-exposed mice with enhanced working memory." in: Physiological research, Vol. 68, Issue 1, pp. 107-117, (2019) (PubMed).

Luo, Chen, Lu, Fu, Lu, Xu, Li, He, Guo: "Baclofen ameliorates spatial working memory impairments induced by chronic cerebral hypoperfusion via up-regulation of HCN2 expression in the PFC in rats." in: Behavioural brain research, Vol. 308, pp. 6-13, (2016) (PubMed).

Luo, Lu, Li, Zhou, Chen, Lu, Xu, He, Guo: "Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region." in: Neurobiology of learning and memory, Vol. 123, pp. 72-83, (2015) (PubMed).

Weltzien, Percival, Martin, Grünert: "Analysis of bipolar and amacrine populations in marmoset retina." in: The Journal of comparative neurology, Vol. 523, Issue 2, pp. 313-34, (2014) (PubMed).

Zhang, Bonnan, Bony, Ferezou, Pietropaolo, Ginger, Sans, Rossier, Oostra, LeMasson, Frick: "Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1701-9, (2014) (PubMed).

Pan, Bhattarai, Modestou, Drack, Chetkovich, Baker: "TRIP8b is required for maximal expression of HCN1 in the mouse retina." in: PLoS ONE, Vol. 9, Issue 1, pp. e85850, (2014) (PubMed).

Liu, Manis, Davis: "I h and HCN channels in murine spiral ganglion neurons: tonotopic variation, local heterogeneity, and kinetic model." in: Journal of the Association for Research in Otolaryngology : JARO, Vol. 15, Issue 4, pp. 585-99, (2014) (PubMed).

Kupferman, Basu, Russo, Guevarra, Cheung, Siegelbaum: "Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment." in: Cell, Vol. 158, Issue 6, pp. 1335-47, (2014) (PubMed).

Li, Lu, Zhou, Zong, Li, Xu, Guo, Lu: "Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion." in: Molecular neurobiology, Vol. 50, Issue 2, pp. 704-20, (2014) (PubMed).

Zhou, Luo, Lu, Li, Wang, Lu, Xu, He, Guo: "Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 56, pp. 207-14, (2014) (PubMed).

Synonyms and alternative names related to HCN1

hyperpolarization activated cyclic nucleotide gated potassium channel 1 (hcn1), hyperpolarization activated cyclic nucleotide gated potassium channel 1 (HCN1), hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 (Hcn1), hyperpolarization-activated, cyclic nucleotide-gated K+ 1 (Hcn1), BCNG-1, BCNG1, Bcng1, C630013B14Rik, HAC-2, HAC2

Protein level used designations for HCN1

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 1
  • brain cyclic nucleotide gated channel 1
  • brain cyclic nucleotide-gated channel 1
  • potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
  • hyperpolarization-activated cyclic nucleotide-gated channel 1
  • rbHCN1
  • BCNG-1
  • HAC-2
  • hyperpolarization-activated cation channel 2
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