HCK Products
(Hemopoietic Cell Kinase (HCK))
Categories
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010].
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Featured HCK Categories
HCK Antibodies
High quality antibodies with extensive validation data.
HCK ELISA Kits
Reliable ELISA kits for a wide range of species.
HCK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HCK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7443947
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, PLA
Validations
- (5)
Cat. No.
ABIN516368
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (4)
Cat. No.
ABIN947963
Quantity
100 μL
Datasheet
Datasheet
Recommended HCK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967343
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956475
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4886120
Quantity
96 tests
Datasheet
Datasheet
Recommended HCK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306427
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306425
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508953
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our HCK products
: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "What I learned in Europe...." in: Environmental science & technology, Vol. 41, Issue 3, pp. 667, (2007) (PubMed).
: "Hyper-CK-emia in pediatric celiac disease: prevalence and clinical importance." in: Journal of clinical gastroenterology, Vol. 41, Issue 7, pp. 667-70, (2007) (PubMed).
: "Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes." in: Blood, Vol. 101, Issue 5, pp. 1874-81, (2003) (PubMed).
: "CSF-induced and HIV-1-mediated distinct regulation of Hck and C/EBPbeta represent a heterogeneous susceptibility of monocyte-derived macrophages to M-tropic HIV-1 infection." in: The Journal of experimental medicine, Vol. 198, Issue 3, pp. 443-53, (2003) (PubMed).
: "The interaction of the Bcr-Abl tyrosine kinase with the Src kinase Hck is mediated by multiple binding domains." in: Leukemia, Vol. 17, Issue 2, pp. 283-9, (2003) (PubMed).
: "The role of Vif during HIV-1 infection: interaction with novel host cellular factors." in: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, Vol. 26, Issue 2, pp. 143-52, (2003) (PubMed).
: "Tyrosine kinase activation in response to fungal spores is primarily dependent on endogenous reactive oxygen production in macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10175-81, (2000) (PubMed).
: "SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in Rat-2 fibroblasts." in: The Journal of biological chemistry, Vol. 274, Issue 37, pp. 26579-83, (1999) (PubMed).
Synonyms and alternative names related to HCK
HCK proto-oncogene, Src family tyrosine kinase L homeolog (hck.L), HCK proto-oncogene, Src family tyrosine kinase (HCK), HCK proto-oncogene, Src family tyrosine kinase (hck), hemopoietic cell kinase (Hck), HCK proto-oncogene, Src family tyrosine kinase (Hck), AI849071, Bmk, HCK, Hctk, JTK9, laloo, MGC107870, p56Hck, p59Hck, p61HckProtein level used designations for HCK
- hemopoietic cell kinase
- non-receptor protein tyrosine kinase laloo
- tyrosine-protein kinase HCK-like
- hematopoietic cell kinase
- p59-HCK/p60-HCK
- tyrosine-protein kinase HCK
- B cell/myeloid kinase
- B-cell/myeloid kinase
- p56-HCK/p59-HCK
- hemopoietic cell tyrosine kinase
- p56-HCK
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