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HCAR2 Products

(Hydroxycarboxylic Acid Receptor 2 (HCAR2))

Categories

putative G-protein coupled receptor for nicotinic acid

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Featured HCAR2 Categories

HCAR2 Antibodies

High quality antibodies with extensive validation data.

HCAR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended HCAR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238999
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN7267804
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN656596
Quantity 400 μL
Datasheet Datasheet

Recommended HCAR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1137666
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1137668
Quantity 96 tests
Datasheet Datasheet

Recommended HCAR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Mammalian Cells
Validations
Cat. No. ABIN7538324
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3116853
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3129722
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HCAR2 products

Gautam, Banskota, Shah, Jee, Kwon, Wang, Kim, Chang, Kim: "4-Hydroxynonenal-induced GPR109A (HCA2 receptor) activation elicits bipolar responses, Gαi -mediated anti-inflammatory effects and Gβγ -mediated cell death." in: British journal of pharmacology, Vol. 175, Issue 13, pp. 2581-2598, (2018) (PubMed).

Chen, So, Li, Cheng, Boucher, Leung: "Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets." in: Molecular and cellular endocrinology, Vol. 404, pp. 56-66, (2015) (PubMed).

Wong, Chan, Leung: "Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice." in: Nutrients, Vol. 7, Issue 9, pp. 7543-61, (2015) (PubMed).

Fu, Wang, Xue, Liu, Liu, Zeng, Li, Huang, Lv, Wang, Liu: "Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms." in: Journal of neuroinflammation, Vol. 12, pp. 9, (2015) (PubMed).

Cresci, Bush, Nagy: "Tributyrin supplementation protects mice from acute ethanol-induced gut injury." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 6, pp. 1489-501, (2014) (PubMed).

Singh, Gurav, Sivaprakasam, Brady, Padia, Shi, Thangaraju, Prasad, Manicassamy, Munn, Lee, Offermanns, Ganapathy: "Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis." in: Immunity, Vol. 40, Issue 1, pp. 128-39, (2014) (PubMed).

Kostylina, Simon, Fey, Yousefi, Simon: "Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)." in: Cell death and differentiation, Vol. 15, Issue 1, pp. 134-42, (2007) (PubMed).

Synonyms and alternative names related to HCAR2

hydroxycarboxylic acid receptor 2 (HCAR2), hydroxycarboxylic acid receptor 2 (Hcar2), hydroxycarboxylic acid receptor 2 (LOC527744), GPR109A, Gpr109a, Gpr109b, HCA2, Hcar2, HCAR2, HCAR3, HM74, HM74a, HM74b, mHM74b, NIACR1, Puma-g, PUMA-G, PUMAG, Pumag

Protein level used designations for HCAR2

  • G protein-coupled receptor 109A
  • G protein-coupled receptor HM74a
  • G-protein coupled receptor 109A
  • G-protein coupled receptor HM74A
  • hydroxy-carboxylic acid receptor 2
  • niacin receptor 1
  • nicotinic acid receptor
  • G protein-coupled receptor 109B
  • G-protein coupled receptor 109
  • G-protein coupled receptor HM74
  • hydroxycarboxylic acid receptor 2
  • interferon-gamma inducible gene, Puma-g
  • putative seven transmembrane spanning receptor
  • hydroxycarboxylic acid receptor 3
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