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H2AFZ Products

(H2A Histone Family, Member Z (H2AFZ))
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008].

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Featured H2AFZ Categories

H2AFZ Antibodies

High quality antibodies with extensive validation data.

H2AFZ ELISA Kits

Reliable ELISA kits for a wide range of species.

H2AFZ Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended H2AFZ Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC, ChIP, IP
Validations
  • (5)
Cat. No. ABIN7139193
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC, ChIP, IP
Validations
  • (5)
Cat. No. ABIN7139181
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, ChIP, IP, IHC (p), IHC (wm)
Validations
  • (5)
Cat. No. ABIN2856585
Quantity 100 μL
Datasheet Datasheet

Recommended H2AFZ ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956384
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5654930
Quantity 96 tests
Datasheet Datasheet

Recommended H2AFZ Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1779451
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129571
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416337
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our H2AFZ products

Akdogan-Ozdilek, Duval, Meng, Murphy, Goll: "Identification of chromatin states during zebrafish gastrulation using CUT&RUN and CUT&Tag." in: Developmental dynamics : an official publication of the American Association of Anatomists, (2021) (PubMed).

Piquet, Le Parc, Bai, Chevallier, Adam, Polo: "The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage." in: Molecular cell, Vol. 72, Issue 5, pp. 888-901.e7, (2018) (PubMed).

Law, Cheung: "Expression of Non-acetylatable H2A.Z in Myoblast Cells Blocks Myoblast Differentiation through Disruption of MyoD Expression." in: The Journal of biological chemistry, Vol. 290, Issue 21, pp. 13234-49, (2015) (PubMed).

Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).

Gemma, Ramagopalan, Down, Beyan, Hawa, Holland, Hurd, Giovannoni, Leslie, Ebers, Rakyan: "Inactive or moderately active human promoters are enriched for inter-individual epialleles." in: Genome biology, Vol. 14, Issue 5, pp. R43, (2014) (PubMed).

Menet, Pescatore, Rosbash: "CLOCK:BMAL1 is a pioneer-like transcription factor." in: Genes & development, Vol. 28, Issue 1, pp. 8-13, (2014) (PubMed).

Boyarchuk, Filipescu, Vassias, Cantaloube, Almouzni: "The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle." in: Journal of cell science, Vol. 127, Issue Pt 15, pp. 3347-59, (2014) (PubMed).

Lodhi, Kossenkov, Tulin: "Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark." in: Nucleic acids research, Vol. 42, Issue 11, pp. 7028-38, (2014) (PubMed).

Lau, Cheung: "Elucidating combinatorial histone modifications and crosstalks by coupling histone-modifying enzyme with biotin ligase activity." in: Nucleic acids research, Vol. 41, Issue 3, pp. e49, (2013) (PubMed).

Vierstra, Wang, John, Sandstrom, Stamatoyannopoulos: "Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH." in: Nature methods, Vol. 11, Issue 1, pp. 66-72, (2013) (PubMed).

Synonyms and alternative names related to H2AFZ

H2A histone family member Z (H2AFZ), H2A histone family, member Z (H2afz), H2A histone family, member Z (H2AFZ), H2A histone family member Z L homeolog (h2afz.L), histone H2A.Z (H2AFZ), H2A.z, H2A.Z, H2A.Z-1, H2a.z-1, h2a.zl1, h2a.zl2, H2A/z, H2AFV, H2AZ, H2Az, XH2AZ

Protein level used designations for H2AFZ

  • H2AZ histone
  • histone H2A.Z
  • H2A/z
  • H2A histone family, member Z
  • H2A histone family, member V
  • H2A.Z1
  • H2A.Zl
  • histone H2A.Z-like
  • histone H2A.Zl2
  • histone H2AF
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