H13 Products
(Histocompatibility 13 (H13))
Categories
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured H13 Categories
H13 Antibodies
High quality antibodies with extensive validation data.
H13 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended H13 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7159822
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
- (2)
Cat. No.
ABIN1387572
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat, Xenopus laevis
Application
WB
Validations
- (1)
Cat. No.
ABIN6746312
Quantity
100 μL
Datasheet
Datasheet
Recommended H13 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306780
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3116824
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3129341
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our H13 products
: "A protease-independent function for SPPL3 in NFAT activation." in: Molecular and cellular biology, Vol. 35, Issue 2, pp. 451-67, (2014) (PubMed).: "Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15153-60, (2004) (PubMed).
: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).
: "Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development." in: Gene expression patterns : GEP, Vol. 3, Issue 5, pp. 685-91, (2003) (PubMed).
Synonyms and alternative names related to H13
histocompatibility minor 13 (HM13), histocompatibility (minor) 13 (hm13), histocompatibility (minor) 13 L homeolog (hm13.L), histocompatibility 13 (H13), histocompatibility minor 13 (Hm13), 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, AV020344, cb228, dJ324O17.1, H-13, H13, h13, Hm13, IMP1, IMPAS, IMPAS-1, MGC68919, MSTP086, PSENL3, PSL3, SPP, Spp, SPPL1, wu:fc11a06, zgc:56660, zgc:86862Protein level used designations for H13
- IMP-1
- hIMP1
- intramembrane protease 1
- minor histocompatibility antigen 13
- minor histocompatibility antigen H13
- presenilin-like protein 3
- signal peptide peptidase beta
- signal peptide peptidase like 1
- histocompatibility 13
- signal peptide peptidase
- intramembrane aspartyl protease
- histocompatibility (minor) 13
- presenilin-like aspartyl protease
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