HAX1 Products
(HCLS1 Associated Protein X-1 (HAX1))
Categories
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured HAX1 Categories
HAX1 Antibodies
High quality antibodies with extensive validation data.
HAX1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HAX1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HAX1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN2855251
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7154840
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7261502
Quantity
200 μL
Datasheet
Datasheet
Recommended HAX1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1136117
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1136116
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1136118
Quantity
96 tests
Datasheet
Datasheet
Recommended HAX1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306379
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306381
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN1098543
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our HAX1 products
: "Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration." in: Genes & cancer, Vol. 5, Issue 3-4, pp. 84-99, (2014) (PubMed).: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).
: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).
Synonyms and alternative names related to HAX1
HCLS1 associated protein X-1 (HAX1), HCLS1 associated protein X-1 (hax1), HCLS1 associated protein X-1 (Hax1), HCLS1 associated X-1 (Hax1), HAX-1, HAX1, hax1, HCLSBP1, HS1BP1, Hs1bp1, HSP1BP-1, mHAX-1s, SCN3, SIG-111, Silg111Protein level used designations for HAX1
- HCLS1 associated protein X-1
- HCLS1-associated protein X-1
- HAX-1
- HCLS1 (and PKD2) associated protein
- HS1 binding protein
- HS1-associating protein X-1
- HS1-binding protein 1
- HSP1BP-1
- HS1-associated protein X-1
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