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HAT Products

(Histone Acetyltransferase (HAT))
This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008].

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Featured HAT Categories

HAT Antibodies

High quality antibodies with extensive validation data.

HAT ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended HAT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2143087
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN1533428
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN1848824
Quantity 100 μL
Datasheet Datasheet

Recommended HAT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381186
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our HAT products

Stewart, Ramani, Sanderson: "Shed Syndecan-1 Translocates to the Nucleus of Cells Delivering Growth Factors and Inhibiting Histone Acetylation: A Novel Mechanism of Tumor-Host Crosstalk." in: The Journal of biological chemistry, (2014) (PubMed).

Khalyfa, Mutskov, Carreras, Khalyfa, Hakim, Gozal: "Sleep fragmentation during late gestation induces metabolic perturbations and epigenetic changes in adiponectin gene expression in male adult offspring mice." in: Diabetes, Vol. 63, Issue 10, pp. 3230-41, (2014) (PubMed).

Vecellio, Spallotta, Nanni, Colussi, Cencioni, Derlet, Bassetti, Tilenni, Carena, Farsetti, Sbardella, Castellano, Mai, Martelli, Pompilio, Capogrossi, Rossini, Dimmeler, Zeiher, Gaetano: "The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients." in: Diabetes, Vol. 63, Issue 6, pp. 2132-47, (2014) (PubMed).

Wang, Chiu, Neumaier, Wang, Zhang, Hussein, Lal, Wan, Liu, Vlodavsky, Rodrigues: "Endothelial cell heparanase taken up by cardiomyocytes regulates lipoprotein lipase transfer to the coronary lumen after diabetes." in: Diabetes, Vol. 63, Issue 8, pp. 2643-55, (2014) (PubMed).

Yang, Li, Chen, Yuan, Dong, Zhang, Wu, Wang: "PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).

Rokudai, Laptenko, Arnal, Taya, Kitabayashi, Prives: "MOZ increases p53 acetylation and premature senescence through its complex formation with PML." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 10, pp. 3895-900, (2013) (PubMed).

Colussi, Rosati, Straino, Spallotta, Berni, Stilli, Rossi, Musso, Macchi, Mai, Sbardella, Castellano, Chimenti, Frustaci, Nebbioso, Altucci, Capogrossi, Gaetano: "Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 7, pp. 2795-800, (2011) (PubMed).

Bourguignon, Xia, Wong et al.: "Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance ..." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 2657-71, (2009) (PubMed).

Choi, Jung, Lee, Yoon, Kwon, Kang, Kim, Cha, Kim, Jun, Lee, Yoon: "Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation." in: Cancer research, Vol. 69, Issue 2, pp. 583-92, (2009) (PubMed).

Ko, Puglielli: "Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels." in: The Journal of biological chemistry, Vol. 284, Issue 4, pp. 2482-92, (2009) (PubMed).

Synonyms and alternative names related to HAT

transmembrane protease, serine 11D (TMPRSS11D), histone acetyltransferase (hat), histone acetyltransferase (HAT), HAT

Protein level used designations for HAT

  • airway trypsin like protease
  • airway trypsin-like protease
  • transmembrane protease serine 11D
  • histone acetyltransferase
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