Haptoglobin Proteins
(Haptoglobin (HP))
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
HP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
recommended
HP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
recommended
Haptoglobin Proteins by Source
Here you will find Haptoglobin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.
Haptoglobin Proteins by Protein Type
Here you can find Haptoglobin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.
Haptoglobin Proteins by Application
Find Haptoglobin Proteins validated for a specific application such as SDS, ELISA, WB, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.
Popular Haptoglobin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123252
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307018
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human
Validations
- (2)
- (1)
Cat. No.
ABIN3119693
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505808
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN1945383
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2129769
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318556
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7318557
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7392218
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7402730
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7411354
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7392227
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417549
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417552
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Haptoglobin Proteins
: "Divergent roles of haptoglobin and hemopexin deficiency for disease progression of Shiga-toxin-induced hemolytic-uremic syndrome in mice." in: Kidney international, (2022) (PubMed).: "Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease." in: American journal of physiology. Cell physiology, Vol. 312, Issue 6, pp. C733-C740, (2017) (PubMed).
: "Study of structure-dependent chromatographic behavior of glycopeptides using reversed phase nanoLC." in: Electrophoresis, Vol. 38, Issue 17, pp. 2193-2199, (2017) (PubMed).
: "IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections." in: Science immunology, Vol. 2, Issue 8, (2017) (PubMed).
: "Interactions of Haptoglobin with Monomeric Globin Species: Insights from Molecular Modeling and Native Electrospray Ionization Mass Spectrometry." in: Biochemistry, Vol. 55, Issue 12, pp. 1918-28, (2016) (PubMed).
: "Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin." in: Journal of neurochemistry, Vol. 139, Issue 4, pp. 586-595, (2016) (PubMed).
: "Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea." in: Blood, Vol. 126, Issue 6, pp. 711-20, (2015) (PubMed).
: "Iron-regulated surface determinant (Isd) proteins of Staphylococcus lugdunensis." in: Journal of bacteriology, Vol. 194, Issue 23, pp. 6453-67, (2012) (PubMed).
Aliases for Haptoglobin Proteins
haptoglobin (HP) Proteinshaptoglobin (hp) Proteins
haptoglobin (Hp) Proteins
haptoglobin-like (LOC479668) Proteins
haptoglobin (LOC101102413) Proteins
BP Proteins
HP Proteins
HP-1 Proteins
HP2ALPHA2 Proteins
HPA1S Proteins
HPR Proteins
wu:fb64e01 Proteins
Zonulin Proteins
Did you look for something else?
- HAPLN4 Proteins
- HAPLN3 Proteins
- HAPLN2 Proteins
- HAPLN1 Proteins
- HAP1 Proteins
- HAO1 Proteins
- HAND2 Proteins
- HAND1 Proteins
- HAL Proteins
- Hairy and Enhancer of Split 4 Proteins
- Hairless Proteins
- HAGHL Proteins
- HAGH Proteins
- HADHB Proteins
- HADHA Proteins
- HADH Proteins
- HACL1 Proteins
- HACE1 Proteins
- HABP4 Proteins
- HABP2 Proteins
- Haptoglobin beta Chain Proteins
- HARBI1 Proteins
- HARS1/Jo-1 Proteins
- HARS2 Proteins
- HAS1 Proteins
- HAS2 Proteins
- HAS3 Proteins
- HAT1 Proteins
- HAUS1 Proteins
- HAUS2 Proteins
- HAUS7 Proteins
- HAX1 Proteins
- HBA1 Proteins
- HbA1c Proteins
- HBd Proteins
- HBEGF Proteins
- HBG1 Proteins
- HBG2 Proteins
- HBP1 Proteins
- HBQ1 Proteins
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