Haptoglobin Products
(Haptoglobin (HP))
Categories
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Haptoglobin Categories
Haptoglobin Antibodies
High quality antibodies with extensive validation data.
Haptoglobin ELISA Kits
Reliable ELISA kits for a wide range of species.
Haptoglobin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Haptoglobin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7429064
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7443863
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Pig
Application
WB, IHC, IP, ICC
Validations
- (10)
Cat. No.
ABIN7432676
Quantity
100 μL
Datasheet
Datasheet
Recommended Haptoglobin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (6)
Cat. No.
ABIN6574216
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN6574217
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (5)
Cat. No.
ABIN6574215
Quantity
96 tests
Datasheet
Datasheet
Recommended Haptoglobin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123252
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1307018
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human
Validations
- (2)
- (1)
Cat. No.
ABIN3119693
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Haptoglobin products
: "Divergent roles of haptoglobin and hemopexin deficiency for disease progression of Shiga-toxin-induced hemolytic-uremic syndrome in mice." in: Kidney international, (2022) (PubMed).: "Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients." in: Cells, Vol. 11, Issue 1, (2022) (PubMed).
: "Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism." in: Nitric oxide : biology and chemistry, Vol. 96, pp. 20-28, (2020) (PubMed).
: "Prolyl endopeptidase-degraded low immunoreactive wheat flour attenuates immune responses in Caco-2 intestinal cells and gluten-sensitized BALB/c mice." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 129, pp. 466-475, (2019) (PubMed).
: "Agreement between commercial assays for haptoglobin and serum amyloid A in goats." in: Acta veterinaria Scandinavica, Vol. 59, Issue 1, pp. 65, (2018) (PubMed).
: "Exploration of differentially expressed plasma proteins in patients with lung adenocarcinoma using iTRAQ-coupled 2D LC-MS/MS." in: The clinical respiratory journal, Vol. 12, Issue 6, pp. 2036-2045, (2018) (PubMed).
: "Isoquinoline alkaloids supplementation on performance and carcass traits of feedlot bulls." in: Asian-Australasian journal of animal sciences, Vol. 31, Issue 9, pp. 1474-1480, (2018) (PubMed).
: "Sulfasalazine treatment can cause a positive effect on LPS-induced endotoxic rats." in: Experimental animals, Vol. 67, Issue 4, pp. 403-412, (2018) (PubMed).
: "High complement levels in astrocyte-derived exosomes of Alzheimer disease." in: Annals of neurology, Vol. 83, Issue 3, pp. 544-552, (2018) (PubMed).
: "Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease." in: American journal of physiology. Cell physiology, Vol. 312, Issue 6, pp. C733-C740, (2017) (PubMed).
Synonyms and alternative names related to Haptoglobin
haptoglobin (HP), haptoglobin (hp), haptoglobin (Hp), haptoglobin-like (LOC479668), haptoglobin (LOC101102413), BP, HP, HP-1, HP2ALPHA2, HPA1S, HPR, wu:fb64e01, ZonulinProtein level used designations for Haptoglobin
- haptoglobin
- HpL
- binding peptide
- haptoglobin alpha(1S)-beta
- haptoglobin alpha(2FS)-beta
- haptoglobin, alpha polypeptide
- haptoglobin, beta polypeptide
- zonulin
- liver regeneration-related protein LRRG173
- haptoglobin-related protein
- haptoglobin alpha 1S
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