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Haptoglobin Products

(Haptoglobin (HP))

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This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured Haptoglobin Categories

Haptoglobin Antibodies

High quality antibodies with extensive validation data.

Haptoglobin ELISA Kits

Reliable ELISA kits for a wide range of species.

Haptoglobin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Haptoglobin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7429064
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7443863
Quantity 100 μL
Datasheet Datasheet
Reactivity Pig
Application WB, IHC, IP, ICC
Validations
  • (10)
Cat. No. ABIN7432676
Quantity 100 μL
Datasheet Datasheet

Recommended Haptoglobin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (6)
Cat. No. ABIN6574216
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (6)
Cat. No. ABIN6574217
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (5)
Cat. No. ABIN6574215
Quantity 96 tests
Datasheet Datasheet

Recommended Haptoglobin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123252
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307018
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human
Validations
  • (2)
  • (1)
Cat. No. ABIN3119693
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Haptoglobin products

Pirschel, Mestekemper, Wissuwa, Krieg, Kröller, Daniel, Gunzer, Tolosano, Bauer, Amann, Heinemann, Coldewey: "Divergent roles of haptoglobin and hemopexin deficiency for disease progression of Shiga-toxin-induced hemolytic-uremic syndrome in mice." in: Kidney international, (2022) (PubMed).

Higham, Baker, Jackson, Shah, Lea, Singh: "Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients." in: Cells, Vol. 11, Issue 1, (2022) (PubMed).

Kline, Puskarich, Pike, Zagorski, Alves: "Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism." in: Nitric oxide : biology and chemistry, Vol. 96, pp. 20-28, (2020) (PubMed).

Mohan Kumar, Vijaykrishnaraj, Kurrey, Shinde, Prabhasankar: "Prolyl endopeptidase-degraded low immunoreactive wheat flour attenuates immune responses in Caco-2 intestinal cells and gluten-sensitized BALB/c mice." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 129, pp. 466-475, (2019) (PubMed).

Czopowicz, Szaluś-Jordanow, Mickiewicz, Moroz, Witkowski, Markowska-Daniel, Reczyńska, Bagnicka, Kaba: "Agreement between commercial assays for haptoglobin and serum amyloid A in goats." in: Acta veterinaria Scandinavica, Vol. 59, Issue 1, pp. 65, (2018) (PubMed).

Li, Zheng, Qin, Liu, Ke, Li, Li, Zhong: "Exploration of differentially expressed plasma proteins in patients with lung adenocarcinoma using iTRAQ-coupled 2D LC-MS/MS." in: The clinical respiratory journal, Vol. 12, Issue 6, pp. 2036-2045, (2018) (PubMed).

Michels, Neumann, Mattos Leão, Reck, Bertagnon, Lopes, de Souza, Santos, Stadler Júnior: "Isoquinoline alkaloids supplementation on performance and carcass traits of feedlot bulls." in: Asian-Australasian journal of animal sciences, Vol. 31, Issue 9, pp. 1474-1480, (2018) (PubMed).

Dik, Sonmez, Faki, Bahcivan: "Sulfasalazine treatment can cause a positive effect on LPS-induced endotoxic rats." in: Experimental animals, Vol. 67, Issue 4, pp. 403-412, (2018) (PubMed).

Goetzl, Schwartz, Abner, Jicha, Kapogiannis: "High complement levels in astrocyte-derived exosomes of Alzheimer disease." in: Annals of neurology, Vol. 83, Issue 3, pp. 544-552, (2018) (PubMed).

Eshbach, Kaur, Rbaibi, Tejero, Weisz: "Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease." in: American journal of physiology. Cell physiology, Vol. 312, Issue 6, pp. C733-C740, (2017) (PubMed).

Synonyms and alternative names related to Haptoglobin

haptoglobin (HP), haptoglobin (hp), haptoglobin (Hp), haptoglobin-like (LOC479668), haptoglobin (LOC101102413), BP, HP, HP-1, HP2ALPHA2, HPA1S, HPR, wu:fb64e01, Zonulin

Protein level used designations for Haptoglobin

  • haptoglobin
  • HpL
  • binding peptide
  • haptoglobin alpha(1S)-beta
  • haptoglobin alpha(2FS)-beta
  • haptoglobin, alpha polypeptide
  • haptoglobin, beta polypeptide
  • zonulin
  • liver regeneration-related protein LRRG173
  • haptoglobin-related protein
  • haptoglobin alpha 1S
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