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HAND1 Products

(Heart and Neural Crest Derivatives Expressed 1 (HAND1))
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008].

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Featured HAND1 Categories

HAND1 Antibodies

High quality antibodies with extensive validation data.

HAND1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HAND1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HAND1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7443566
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC
Validations
  • (3)
Cat. No. ABIN7248206
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7154845
Quantity 100 μL
Datasheet Datasheet

Recommended HAND1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883165
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1136128
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1136130
Quantity 96 tests
Datasheet Datasheet

Recommended HAND1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306339
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129581
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418560
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HAND1 products

Lu, Du, Shan, Wang, Ma, Dong: "Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture." in: Biochemical and biophysical research communications, Vol. 478, Issue 4, pp. 1726-31, (2016) (PubMed).

Zhang, Chen, Ye, Wang, Wang, Yuan, Lin, Wu, Zhang, Lin: "Wnt signaling promotes hindgut fate commitment through regulating multi-lineage genes during hESC differentiation." in: Cellular signalling, Vol. 29, pp. 12-22, (2016) (PubMed).

Kobayashi, Yoshida, Tarui, Hirata, Nagai, Kasahara, Naruse, Ito, Sano, Oh et al.: "Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left ..." in: PLoS ONE, Vol. 9, Issue 7, pp. e102796, (2014) (PubMed).

Friese, Altshuler, Zhang, Miramontes-Gonzalez, Hightower, Jirout, Salem, Gayen, Mahapatra, Biswas, Cale, Vaingankar, Kim, Courel, Taupenot, Ziegler, Schork, Pravenec, Mahata, Schmid-Schönbein, OConnor: "MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3624-40, (2013) (PubMed).

Reichman, Kalathur, Lambard, Aït-Ali, Yang, Lardenois, Ripp, Poch, Zack, Sahel, Léveillard: "The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina." in: Human molecular genetics, Vol. 19, Issue 2, pp. 250-61, (2009) (PubMed).

Lexer, Welch, Durphy, Rieseberg: "Natural selection for salt tolerance quantitative trait loci (QTLs) in wild sunflower hybrids: implications for the origin of Helianthus paradoxus, a diploid hybrid species." in: Molecular ecology, Vol. 12, Issue 5, pp. 1225-35, (2003) (PubMed).

Firulli, Howard, McDaid, McIlreavey, Dionne, Centonze, Cserjesi, Virshup, Firulli: "PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation." in: Molecular cell, Vol. 12, Issue 5, pp. 1225-37, (2003) (PubMed).

Dai, Cserjesi: "The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12604-12, (2002) (PubMed).

Synonyms and alternative names related to HAND1

cathepsin G (CTSG), heart and neural crest derivatives expressed 1 (HAND1), heart and neural crest derivatives expressed 1 (Hand1), heart and neural crest derivatives expressed 1 L homeolog (hand1.L), heart and neural crest derivatives expressed 1 (hand1), bHLHa27, CATG, CG, eHand, eHAND, EHAND, Ehand1, hand-1, HAND1, Hand1, hand1-A, Hxt, HXT, hxt, Th1, Thing1, thing1

Protein level used designations for HAND1

  • class A basic helix-loop-helix protein 27
  • extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1
  • heart- and neural crest derivatives-expressed protein 1
  • heart and neural crest derivatives expressed transcript 1
  • heart and neural crest derivatives-expressed protein 1
  • eHAND
  • heart and neural crest derivatives expressed 1
  • basic helix-loop-helix transcription factor HAND1
  • eHAND basic helix-loop-helix transcription factor
  • Heart- and neural crest derivatives-expressed protein 1
  • helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast
  • thing-1
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