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Hairy and Enhancer of Split 4 Proteins

(Hairy and Enhancer of Split 4 (HES4))

Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Promotes floor plate development and prechordal plate development. Required for lens development as early as the stage of lens field formation, partly through regulation of gene expression of the cell cycle inhibitor cdknx/p27(xic1). Required for formation of the neural crest downstream of multiple signaling pathways, and acts at the neural plate border via both DNA-binding dependent and independent mechanisms. Also acts via repressor- dependent and repressor-independent mechanisms in early gastrulae to establish the prospective anterior prechordal mesoderm identity in the Spemann organizer\; induces specific genes independently from direct transcriptional regulation, and represses the genes specific for neighboring tissues through direct transcriptional repression. Modulates lateral inhibition during notch signaling and regulates the cell context dependent effects of notch (which can have inhibitory, permissive or enhancing roles in muscle or neural differentiation). Inhibits myogenesis (By similarity).

recommended

HES4 Protein (AA 1-221) (GST tag) (ABIN1306551)

HES4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

HES4 Protein (AA 1-221) (Strep Tag) (ABIN3081428)

HES4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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recommended

HES4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722664)

HES4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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Hairy and Enhancer of Split 4 Proteins by Origin

Find Hairy and Enhancer of Split 4 Proteins for a variety of species such as anti-Human Hairy and Enhancer of Split 4, anti-Xenopus laevis Hairy and Enhancer of Split 4. The species listed below are among those available. Click on a link to go to the corresponding products.

Hairy and Enhancer of Split 4 Proteins by Source

Here you will find Hairy and Enhancer of Split 4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Hairy and Enhancer of Split 4 Proteins by Protein Type

Here you can find Hairy and Enhancer of Split 4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Hairy and Enhancer of Split 4 Proteins by Application

Find Hairy and Enhancer of Split 4 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Hairy and Enhancer of Split 4 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

HES4 Protein (AA 1-221) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1306551

Quantity 25 μg

Datasheet Datasheet

HES4 Protein (AA 1-221) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3081428

Quantity 1 mg

Datasheet Datasheet

HES4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2722664

Quantity 20 μg

Datasheet Datasheet

HES4 Protein (AA 1-277) (His tag)

Reactivity Xenopus laevis

Source Yeast

Validations

Cat. No. ABIN1639349

Quantity 1 mg

Datasheet Datasheet

HES4 Protein (AA 1-281) (His tag)

Reactivity Xenopus laevis

Source Yeast

Validations

Cat. No. ABIN1640267

Quantity 1 mg

Datasheet Datasheet

Aliases for Hairy and Enhancer of Split 4 Proteins

hes family bHLH transcription factor 4 (HES4) Proteins
hes family bHLH transcription factor 4 (hes4) Proteins
hes family bHLH transcription factor 4 L homeolog (hes4.L) Proteins
hes family bHLH transcription factor 4 S homeolog (hes4.S) Proteins
bHLHb42 Proteins
hairy2 Proteins
hairy2a Proteins
hairy2b Proteins
hes1 Proteins
hes4a Proteins
hes4b Proteins
Xhairy2 Proteins
XHairy2a Proteins
Xhairy2a Proteins
Xhairy2b Proteins

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Hairy and Enhancer of Split 4 Proteins by Origin

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Popular Hairy and Enhancer of Split 4 Proteins

Aliases for Hairy and Enhancer of Split 4 Proteins

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