HADHB Products
(Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))
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This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found\; however, their full-length nature is not known. [provided by RefSeq, Jul 2008].
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Featured HADHB Categories
HADHB Antibodies
High quality antibodies with extensive validation data.
HADHB ELISA Kits
Reliable ELISA kits for a wide range of species.
HADHB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HADHB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN947959
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN516342
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Bat, Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN604755
Quantity
50 μg
Datasheet
Datasheet
Recommended HADHB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956624
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956625
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1163759
Quantity
96 tests
Datasheet
Datasheet
Recommended HADHB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306326
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306325
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN5623911
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our HADHB products
: "Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 329-338, (2019) (PubMed).: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).
: "TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 311, Issue 1, pp. H64-75, (2016) (PubMed).
: "Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33652-61, (2010) (PubMed).
: "Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes." in: Endocrinology, Vol. 151, Issue 1, pp. 123-33, (2009) (PubMed).
Synonyms and alternative names related to HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (HADHB), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta S homeolog (hadhb.S), hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB), hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (Hadhb), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (hadhb), hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (Hadhb), 4930479F15Rik, ECHB, fb14g10, Hadhb, MTPB, Mtpb, thiolase, TP-BETA, wu:fb14g10, zgc:56274Protein level used designations for HADHB
- 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit
- 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit
- acetyl-CoA acyltransferase
- beta-ketothiolase
- hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
- trifunctional enzyme subunit beta, mitochondrial
- hydroxyacyl dehydrogenase, subunit B
- TP-beta
- dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
- mitochondrial trifunctional protein, beta subunit
- 3-ketoacyl-Coenzyme A thiolase
- TP-Beta
- enoyl-Coenzyme A hydratase, beta subunit
- trifunctional enzyme beta subunit, mitochondrial
- dehydrogenase/3-ketoacyl-Coenzyme A thiolase
- hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit
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