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HADHA Products

(Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA))

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This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008].

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Featured HADHA Categories

HADHA Antibodies

High quality antibodies with extensive validation data.

HADHA ELISA Kits

Reliable ELISA kits for a wide range of species.

HADHA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HADHA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN6141585
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN2854961
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN6141586
Quantity 100 μL
Datasheet Datasheet

Recommended HADHA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1163754
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1163755
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1163757
Quantity 96 tests
Datasheet Datasheet

Recommended HADHA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123379
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306324
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our HADHA products

Kakumani, Shanmugam, Kaur, Malhotra, Mukherjee, Bhatnagar: "Association of HADHA with human RNA silencing machinery." in: Biochemical and biophysical research communications, Vol. 466, Issue 3, pp. 481-5, (2015) (PubMed).

Gerin, Clerbaux, Haumont, Lanthier, Das, Burant, Leclercq, MacDougald, Bommer: "Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33652-61, (2010) (PubMed).

Synonyms and alternative names related to HADHA

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha (HADHA), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha (hadha), hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (HADHA), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha S homeolog (hadha.S), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a (hadhaa), hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (Hadha), hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit (Hadha), C77020, cb1055, ECHA, GBP, HADH, hadha, im:7136067, LCEH, LCHAD, MTPA, Mtpa, RGD1560655, TP-ALPHA, wu:fa14c08

Protein level used designations for HADHA

  • trifunctional enzyme subunit alpha, mitochondrial
  • dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit hydroxyacyl-Coenzyme A
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
  • mitochondrial trifunctional protein, alpha subunit
  • CFR-associated protein p70
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein)
  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
  • hydroxyacyl-coenzyme A dehydrogenase/3-ketoacyl-coenzyme A thiolase/enoyl-coenzyme A hydratase (trifunctional protein) alpha subunit
  • mitochondrial trifunctional protein, alpha subunit-like
  • trifunctional enzyme subunit alpha, mitochondrial-like
  • 3-ketoacyl-Coenzyme A (CoA) thiolase, alpha subunit
  • 3-oxoacyl-CoA thiolase
  • 78 kDa gastrin-binding protein
  • gastrin-binding protein
  • long-chain 2-enoyl-CoA hydratase
  • long-chain-3-hydroxyacyl-CoA dehydrogenase
  • mitochondrial long-chain 2-enoyl-Coenzyme A (CoA) hydratase, alpha subunit
  • mitochondrial long-chain L-3-hydroxyacyl-Coenzyme A (CoA) dehydrogenase, alpha subunit
  • mitochondrial trifunctional enzyme, alpha subunit
  • TP-alpha
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