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GZMM Products

(Granzyme M (Lymphocyte Met-Ase 1) (GZMM))
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

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Featured GZMM Categories

GZMM Antibodies

High quality antibodies with extensive validation data.

GZMM ELISA Kits

Reliable ELISA kits for a wide range of species.

GZMM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GZMM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7189462
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN390763
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN1172881
Quantity 100 μL
Datasheet Datasheet

Recommended GZMM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (6)
Cat. No. ABIN6574157
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956304
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN1570217
Quantity 96 tests
Datasheet Datasheet

Recommended GZMM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306275
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306274
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7410796
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GZMM products

Bovenschen, Spijkers, Wensink, Schellens, van Domselaar, van Baarle: "Elevated granzyme M-expressing lymphocytes during cytomegalovirus latency and reactivation after allogeneic stem cell transplantation." in: Clinical immunology (Orlando, Fla.), Vol. 150, Issue 1, pp. 1-11, (2014) (PubMed).

Schiffer, Letzian, Jost, Mladenov, Hristodorov, Huhn, Fischer, Barth, Thepen: "Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells." in: Cancer letters, Vol. 341, Issue 2, pp. 178-85, (2013) (PubMed).

Synonyms and alternative names related to GZMM

granzyme M (LOC100136381), granzyme M (GZMM), granzyme M (Gzmm), granzyme M (lymphocyte met-ase 1) (Gzmm), LMET1, Lmet1, MET1, MMET-1

Protein level used designations for GZMM

  • granzyme M
  • HU-Met-1
  • Met-1 serine protease
  • lymphocyte met-ase 1
  • met-ase
  • natural killer cell granular protease
  • RNK-Met-1
  • lymphoctye Met-ase 1
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