GSTM4 Products
(Glutathione S-Transferase mu 4 (GSTM4))
Categories
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq, Jul 2008].
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Featured GSTM4 Categories
GSTM4 Antibodies
High quality antibodies with extensive validation data.
GSTM4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GSTM4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (11)
Cat. No.
ABIN7439909
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (10)
Cat. No.
ABIN7444301
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IF, FACS, StM
Validations
- (5)
Cat. No.
ABIN6939574
Quantity
100 μg
Datasheet
Datasheet
Recommended GSTM4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229643
Quantity
96 tests
Datasheet
Datasheet
Recommended GSTM4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306087
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306085
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667165
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GSTM4 products
: "Bone Regulation of Insulin Secretion and Glucose Homeostasis." in: Endocrinology, Vol. 161, Issue 10, (2020) (PubMed).: "Screening for inter-individual splicing differences in human GSTM4 and the discovery of a single nucleotide substitution related to the tandem skipping of two exons." in: Gene, Vol. 379, pp. 148-55, (2006) (PubMed).
: "Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4." in: The Journal of biological chemistry, Vol. 268, Issue 23, pp. 16958-65, (1993) (PubMed).
: "Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4." in: The Biochemical journal, Vol. 291 ( Pt 1), pp. 41-50, (1993) (PubMed).
: "Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript." in: The Biochemical journal, Vol. 294 ( Pt 2), pp. 373-80, (1993) (PubMed).
Synonyms and alternative names related to GSTM4
glutathione S-transferase mu 4 (GSTM4), glutathione S-transferase mu 4 (Gstm4), glutathione S-transferase, mu 4 (Gstm4), 1110004G14Rik, Gstb-4, Gstb4, GSTM4-4, GSTM7-7, GTM4Protein level used designations for GSTM4
- glutathione S-transferase M4
- GST class-mu 4
- GST-Mu2
- GTS-Mu2
- S-(hydroxyalkyl)glutathione lyase M4
- glutathione S-alkyltransferase M4
- glutathione S-aralkyltransferase M4
- glutathione S-aryltransferase M4
- glutathione S-transferase Mu 4
- glutathione S-transferase mu 3
- glutathione S-transferase mu 4
- glutathione-S-transferase, mu 4
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