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GSTM3 Products

(Glutathione S-Transferase mu 3 (Brain) (GSTM3))

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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008].

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Featured GSTM3 Categories

GSTM3 Antibodies

High quality antibodies with extensive validation data.

GSTM3 ELISA Kits

Reliable ELISA kits for a wide range of species.

GSTM3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GSTM3 Antibodies

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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
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Cat. No. ABIN5693252
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
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Cat. No. ABIN5708464
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
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Cat. No. ABIN7154107
Quantity 100 μg
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Recommended GSTM3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
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Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6956224
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5654715
Quantity 96 tests
Datasheet Datasheet

Recommended GSTM3 Proteins

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Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1306082
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129548
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405630
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GSTM3 products

Singh, Prasad, Singh, Singh, Gupta, Paliwal, Pandey, Gupta: "Human Glutathione S-Transferase Enzyme Gene Polymorphisms and Their Association With Neurocysticercosis." in: Molecular neurobiology, (2016) (PubMed).

Venkataraman, den Braver, Vermeulen, Commandeur: "Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases." in: Chemical research in toxicology, Vol. 27, Issue 12, pp. 2071-81, (2014) (PubMed).

Hong, Heun, Jessen, Popp, Hentschel, Kelemen, Schulz, Maier, Kölsch: "Gene variations in GSTM3 are a risk factor for Alzheimer's disease." in: Neurobiology of aging, Vol. 30, Issue 5, pp. 691-6, (2009) (PubMed).

Synonyms and alternative names related to GSTM3

glutathione S-transferase mu 3 (GSTM3), glutathione S-transferase Mu 3 (GSTM3), glutathione S-transferase, mu 3 (Gstm3), glutathione S-transferase Mu 3 (LOC479911), glutathione S-transferase mu 3 (Gstm3), Fsc2, GST5, GSTB, GSTM3-3, GTM3, mGSTM5

Protein level used designations for GSTM3

  • GST class-mu 3
  • S-(hydroxyalkyl)glutathione lyase M3
  • brain GST
  • brain type mu-glutathione S-transferase
  • glutathione S-alkyltransferase M3
  • glutathione S-aralkyltransferase M3
  • glutathione S-aryltransferase M3
  • glutathione S-transferase M3 (brain)
  • glutathione S-transferase Mu 3
  • glutathione S-transferase, Mu-3
  • hGSTM3-3
  • glutathione S-transferase M3
  • glutathione S-transferase GT9.3
  • glutathione S-transferase mu 3
  • glutathione-S-transferase, mu
  • glutathione S-transferase Mu 3-like
  • glutathione S-transferase Mu 5
  • GST class-mu 5
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