GSTa2 Products
(Glutathione S-Transferase alpha 2 (GSTa2))
Categories
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008].
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Featured GSTa2 Categories
GSTa2 Antibodies
High quality antibodies with extensive validation data.
GSTa2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GSTa2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GSTa2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7434407
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN516223
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (3)
Cat. No.
ABIN653362
Quantity
400 μL
Datasheet
Datasheet
Recommended GSTa2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967114
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956215
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229637
Quantity
96 tests
Datasheet
Datasheet
Recommended GSTa2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306061
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306063
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7395404
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GSTa2 products
: "Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions." in: Blood advances, Vol. 1, Issue 18, pp. 1440-1451, (2018) (PubMed).: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).
: "Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases." in: Chemical research in toxicology, Vol. 27, Issue 12, pp. 2071-81, (2014) (PubMed).
: "Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis." in: Journal of cellular physiology, Vol. 229, Issue 6, pp. 801-12, (2014) (PubMed).
Synonyms and alternative names related to GSTa2
glutathione S-transferase alpha 2 (GSTA2), glutathione S-transferase alpha 2 (Gsta2), glutathione S-transferase (GSTA2), glutathione S-transferase, alpha 2 (Yc2) (Gsta2), GST2, Gst2-2, GSTA1, Gsta1, GSTA2-2, Gstc-2, Gstc2, GTA2, GTH2Protein level used designations for GSTa2
- GST class-alpha member 1
- GST class-alpha member 2
- glutathione S-transferase A1
- glutathione S-transferase A2
- glutathione S-transferase alpha 1
- glutathione S-transferase alpha-1
- glutathione S-transferase alpha-2
- GST HA subunit 2
- GST-gamma
- S-(hydroxyalkyl)glutathione lyase A2
- glutathione S-alkyltransferase A2
- glutathione S-aralkyltransferase A2
- glutathione S-aryltransferase A2
- liver GST2
- GST 1-1
- GST 1a-1a
- GST A1-1
- GST B
- GST Ya1
- Glutathione-S-transferase alpha type (Yc?)
- glutathione S-transferase Ya subunit
- glutathione S-transferase Ya-1
- glutathione-S-transferase, alpha type2
- ligandin
- glutathione S-transferase alpha class A2
- glutathione S-transferase GT41A
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