GSTA1 Products
(Glutathione S-Transferase alpha 1 (GSTA1))
Categories
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008].
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Featured GSTA1 Categories
GSTA1 Antibodies
High quality antibodies with extensive validation data.
GSTA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
GSTA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GSTA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN7234519
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7432181
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN561158
Quantity
100 μg
Datasheet
Datasheet
Recommended GSTA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6574174
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956213
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967112
Quantity
96 tests
Datasheet
Datasheet
Recommended GSTA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666922
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306059
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN935078
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GSTA1 products
: "Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8787392, (2018) (PubMed).: "Oviductal Transcriptome Is Modified after Insemination during Spontaneous Ovulation in the Sow." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130128, (2015) (PubMed).
: "Comprehensive and temporal analysis of secreted proteins in the medium from IL-6 exposed human hepatocyte." in: Biomedical chromatography : BMC, Vol. 28, Issue 6, pp. 742-50, (2014) (PubMed).
: "Redox protein expression predicts radiotherapeutic response in early-stage invasive breast cancer patients." in: International journal of radiation oncology, biology, physics, Vol. 79, Issue 5, pp. 1532-40, (2011) (PubMed).
: "Early markers of tubular dysfunction in antiretroviral-experienced HIV-infected patients treated with tenofovir versus abacavir." in: AIDS patient care and STDs, Vol. 26, Issue 1, pp. 5-11, (2011) (PubMed).
: "Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy." in: Analytical cellular pathology (Amsterdam), Vol. 34, Issue 3, pp. 131-45, (2011) (PubMed).
: "Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma." in: Cancer research, Vol. 68, Issue 16, pp. 6661-8, (2008) (PubMed).
: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, (1997) (PubMed).
: "Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family." in: Cancer research, Vol. 55, Issue 13, pp. 2737-42, (1995) (PubMed).
Synonyms and alternative names related to GSTA1
glutathione S-transferase alpha 1 (GSTA1), glutathione S-transferase, alpha 1 (Ya) (Gsta1), glutathione S-transferase alpha 3 (GSTA3), glutathione S-transferase alpha 5 (GSTA5), glutathione S-transferase alpha 1 L homeolog (gsta1.L), glutathione S-transferase alpha 1 (gsta1), glutathione S-transferase alpha 2 (Gsta2), glutathione S-transferase mu 2 (muscle) (GSTM2), Glutathione S-transferase 2 (gst-2), glutathione S-transferase A (LOC100713029), glutathione S-transferase Gst2 (gst2), glutathione S-transferase 2 (LOC101897277), GST, Gst-2, Gst-3, GST2, gst2, Gst2, Gst2-1, Gst3, GSTA1, Gsta1, GSTA1-1, gsta1-1, GSTA3, GTH1, gth1, OTTMUSG00000031890Protein level used designations for GSTA1
- GST HA subunit 1
- GST class-alpha member 1
- GST, class alpha, 1
- GST-epsilon
- S-(hydroxyalkyl)glutathione lyase A1
- glutathione S-alkyltransferase A1
- glutathione S-aryltransferase A1
- glutathione S-transferase 2
- glutathione S-transferase A1
- glutathione S-transferase Ha subunit 1
- glutathione S-transferase Ya
- glutathione S-transferase Ya1
- glutathione S-transferase alpha 3
- glutathione S-transferase alpha 1
- glutathione S-transferase alpha-1
- GST class-alpha
- glutathione S-transferase alpha M14
- GST 1-1
- GST 1a-1a
- GST A1-1
- GST B
- GST Ya1
- Glutathione-S-transferase alpha type (Yc?)
- glutathione S-transferase A2
- glutathione S-transferase Ya subunit
- glutathione S-transferase Ya-1
- glutathione-S-transferase, alpha type2
- ligandin
- GST class-mu
- GST-CL2
- GSTM1-1
- glutathione S-transferases CL2
- GST-II
- GST class-theta
- Glutathione S-transferase 3
- glutatione transferase-2
- glutatione transferase-3C
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