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GSDMD Products

(Gasdermin D (GSDMD))

Categories

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009].

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Featured GSDMD Categories

GSDMD Antibodies

High quality antibodies with extensive validation data.

GSDMD ELISA Kits

Reliable ELISA kits for a wide range of species.

GSDMD Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GSDMD Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (6)
Cat. No. ABIN566383
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN7267351
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7267350
Quantity 100 μL
Datasheet Datasheet

Recommended GSDMD ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956056
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956055
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956057
Quantity 96 tests
Datasheet Datasheet

Recommended GSDMD Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123056
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306028
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420990
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GSDMD products

Balaha, Ahmed, Almalki, Alahmari, Alshehri, Soliman, Hamad: "Epimedin A ameliorates DNFB-induced allergic contact dermatitis in mice: Role of NF-κB/NLRP3-driven pyroptosis, Nrf2/HO-1 pathway, and inflammation modulation." in: Life sciences, Vol. 302, pp. 120653, (2022) (PubMed).

Pandori, Lima, Mallya, Kao, Gov, Lodoen: "Toxoplasma gondii activates a Syk-CARD9-NF-κB signaling axis and gasdermin D-independent release of IL-1β during infection of primary human monocytes." in: PLoS pathogens, Vol. 15, Issue 8, pp. e1007923, (2020) (PubMed).

Kulkarni, Elvington, Perng, Liszewski, Byers, Farkouh, Yusen, Lenschow, Brody, Atkinson: "Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death." in: American journal of respiratory cell and molecular biology, Vol. 60, Issue 2, pp. 144-157, (2019) (PubMed).

Kerr, de Rivero Vaccari, Umland, Bullock, Conner, Dietrich, Keane: "Human Lung Cell Pyroptosis Following Traumatic Brain Injury." in: Cells, Vol. 8, Issue 1, (2019) (PubMed).

Burgener, Leborgne, Snipas, Salvesen, Bird, Benarafa: "Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation." in: Cell reports, Vol. 27, Issue 12, pp. 3646-3656.e5, (2019) (PubMed).

Zhang, Shao, Jiang, Mou, Gu, Li, Lin, He, Zhang, Zhou, Ni: "Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury." in: Cell death & disease, Vol. 9, Issue 10, pp. 983, (2018) (PubMed).

Johnson, Taabazuing, Okondo, Chui, Rao, Brown, Reed, Peguero, de Stanchina, Kentsis, Bachovchin: "DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia." in: Nature medicine, Vol. 24, Issue 8, pp. 1151-1156, (2018) (PubMed).

Mejias, Martinez, Stephens, de Rivero Vaccari: "Contribution of the inflammasome to inflammaging." in: Journal of inflammation (London, England), Vol. 15, pp. 23, (2018) (PubMed).

Evavold, Ruan, Tan, Xia, Wu, Kagan: "The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages." in: Immunity, Vol. 48, Issue 1, pp. 35-44.e6, (2018) (PubMed).

Semino, Carta, Gattorno, Sitia, Rubartelli: "Progressive waves of IL-1β release by primary human monocytes via sequential activation of vesicular and gasdermin D-mediated secretory pathways." in: Cell death & disease, Vol. 9, Issue 11, pp. 1088, (2018) (PubMed).

Synonyms and alternative names related to GSDMD

gasdermin D (GSDMD), gasdermin D (Gsdmd), 1810036L03Rik, AW558049, DF5L, DFNA5L, Dfna5l, GSDMD, GSDMDC1, Gsdmdc1, M2-4

Protein level used designations for GSDMD

  • gasdermin domain containing 1
  • gasdermin-D
  • gasdermin D
  • gasdermin domain-containing protein 1
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