Growth Arrest and DNA-Damage-Inducible, beta Products
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008].
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Featured Growth Arrest and DNA-Damage-Inducible, beta Categories
Growth Arrest and DNA-Damage-Inducible, beta Antibodies
High quality antibodies with extensive validation data.
Growth Arrest and DNA-Damage-Inducible, beta Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Growth Arrest and DNA-Damage-Inducible, beta Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application
IHC, WB
Validations
- (5)
- (8)
Cat. No.
ABIN2783334
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN759596
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7154468
Quantity
100 μg
Datasheet
Datasheet
Recommended Growth Arrest and DNA-Damage-Inducible, beta Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN935002
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7318512
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415761
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Growth Arrest and DNA-Damage-Inducible, beta products
: "BDNF rs6265 methylation and genotype interact on risk for schizophrenia. ..." in: Epigenetics, Vol. 11, Issue 1, pp. 11-23, (2016) (PubMed).: "Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors." in: Alcoholism, clinical and experimental research, Vol. 40, Issue 2, pp. 263-72, (2016) (PubMed).
: "Evaluation of protein biomarkers of prostate cancer aggressiveness." in: BMC cancer, Vol. 14, pp. 244, (2014) (PubMed).
: "Neuronal Rac1 is required for learning-evoked neurogenesis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 30, pp. 12229-41, (2013) (PubMed).
: "Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain." in: Molecular pharmacology, Vol. 80, Issue 1, pp. 174-82, (2011) (PubMed).
: "Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 2, pp. 531-42, (2011) (PubMed).
: "Gadd45 beta forms a homodimeric complex that binds tightly to MKK7." in: Journal of molecular biology, Vol. 378, Issue 1, pp. 97-111, (2008) (PubMed).
Synonyms and alternative names related to Growth Arrest and DNA-Damage-Inducible, beta
growth arrest and DNA damage inducible beta (GADD45B), growth arrest and DNA-damage-inducible 45 beta (Gadd45b), growth arrest and DNA-damage-inducible, beta (Gadd45b), growth arrest and DNA-damage-inducible, beta a (gadd45ba), growth arrest and DNA damage inducible beta (Gadd45b), growth arrest and DNA-damage-inducible, beta b (gadd45bb), AI323528, cb196, CS131, gadd45b, gadd45b1, gadd45b2, GADD45BETA, gadd45beta, gadd45bl, MYD118, Myd118, sb:cb196, wu:fa92d10, wu:fa98h12, wu:fk65h03, zgc:73104, zgc:111973, zgc:112453Protein level used designations for Growth Arrest and DNA-Damage-Inducible, beta
- growth arrest and DNA damage-inducible protein GADD45 beta
- myeloid differentiation primary response protein MyD118
- negative growth regulatory protein MyD118
- growth arrest and DNA-damage-inducible protein GADD45 beta
- myeloid differentiation primary response gene 118
- growth arrest and DNA-damage-inducible 45 beta
- gadd
- growth arrest and DNA damage 45 beta
- myeloid differentiation primary response
- Myeloid differentiation primary response protein MyD118
- growth arrest and DNA-damage-inducible, beta b
- growth arrest and DNA-damage-inducible, beta like
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